| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAQ05873.1 | polA | SKA53_07202 | SKA53_15116 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.549 |
| EAQ05873.1 | ruvA | SKA53_07202 | SKA53_08606 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | Holliday junction DNA helicase motor protein; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.667 |
| EAQ05873.1 | ruvB | SKA53_07202 | SKA53_08601 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.636 |
| EAQ06150.1 | EAQ06151.1 | SKA53_08591 | SKA53_08596 | COG0824 Predicted thioesterase. | Hypothetical protein. | 0.855 |
| EAQ06150.1 | ruvA | SKA53_08591 | SKA53_08606 | COG0824 Predicted thioesterase. | Holliday junction DNA helicase motor protein; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.859 |
| EAQ06150.1 | ruvB | SKA53_08591 | SKA53_08601 | COG0824 Predicted thioesterase. | Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.856 |
| EAQ06150.1 | ruvC | SKA53_08591 | SKA53_08611 | COG0824 Predicted thioesterase. | Holliday junction resolvase; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.859 |
| EAQ06151.1 | EAQ06150.1 | SKA53_08596 | SKA53_08591 | Hypothetical protein. | COG0824 Predicted thioesterase. | 0.855 |
| EAQ06151.1 | ruvA | SKA53_08596 | SKA53_08606 | Hypothetical protein. | Holliday junction DNA helicase motor protein; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.876 |
| EAQ06151.1 | ruvB | SKA53_08596 | SKA53_08601 | Hypothetical protein. | Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.855 |
| EAQ06151.1 | ruvC | SKA53_08596 | SKA53_08611 | Hypothetical protein. | Holliday junction resolvase; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.855 |
| EAQ07760.1 | dnaA | SKA53_13023 | SKA53_10549 | FtsK/SpoIIIE family protein; COG1674 DNA segregation ATPase FtsK/SpoIIIE and related proteins. | Chromosomal replication initiation protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | 0.684 |
| EAQ07760.1 | polA | SKA53_13023 | SKA53_15116 | FtsK/SpoIIIE family protein; COG1674 DNA segregation ATPase FtsK/SpoIIIE and related proteins. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.648 |
| EAQ07760.1 | recR | SKA53_13023 | SKA53_15206 | FtsK/SpoIIIE family protein; COG1674 DNA segregation ATPase FtsK/SpoIIIE and related proteins. | Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. | 0.660 |
| EAQ07760.1 | ruvA | SKA53_13023 | SKA53_08606 | FtsK/SpoIIIE family protein; COG1674 DNA segregation ATPase FtsK/SpoIIIE and related proteins. | Holliday junction DNA helicase motor protein; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.634 |
| EAQ07760.1 | ruvB | SKA53_13023 | SKA53_08601 | FtsK/SpoIIIE family protein; COG1674 DNA segregation ATPase FtsK/SpoIIIE and related proteins. | Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.595 |
| EAQ07760.1 | ruvC | SKA53_13023 | SKA53_08611 | FtsK/SpoIIIE family protein; COG1674 DNA segregation ATPase FtsK/SpoIIIE and related proteins. | Holliday junction resolvase; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.458 |
| dnaA | EAQ07760.1 | SKA53_10549 | SKA53_13023 | Chromosomal replication initiation protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | FtsK/SpoIIIE family protein; COG1674 DNA segregation ATPase FtsK/SpoIIIE and related proteins. | 0.684 |
| dnaA | polA | SKA53_10549 | SKA53_15116 | Chromosomal replication initiation protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.597 |
| dnaA | recR | SKA53_10549 | SKA53_15206 | Chromosomal replication initiation protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. | 0.715 |