| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAQ05538.1 | EAQ07143.1 | SKA53_00589 | SKA53_02066 | Oxidoreductase, molybdopterin-binding; COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | Iron-sulfur cluster-binding protein; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. | 0.625 |
| EAQ05538.1 | EAQ07263.1 | SKA53_00589 | SKA53_02666 | Oxidoreductase, molybdopterin-binding; COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. | 0.831 |
| EAQ05538.1 | EAQ07264.1 | SKA53_00589 | SKA53_02671 | Oxidoreductase, molybdopterin-binding; COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | COG0155 Sulfite reductase, beta subunit (hemoprotein). | 0.889 |
| EAQ05538.1 | EAQ07315.1 | SKA53_00589 | SKA53_02926 | Oxidoreductase, molybdopterin-binding; COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits. | 0.907 |
| EAQ05538.1 | EAQ07878.1 | SKA53_00589 | SKA53_09149 | Oxidoreductase, molybdopterin-binding; COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | COG1145 Ferredoxin. | 0.937 |
| EAQ05538.1 | cysC | SKA53_00589 | SKA53_08711 | Oxidoreductase, molybdopterin-binding; COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | Binfunctional sulfate adenylyltransferase subunit 1/adenylylsulfate kinase protein; Catalyzes the synthesis of activated sulfate. | 0.889 |
| EAQ05538.1 | msrP | SKA53_00589 | SKA53_10359 | Oxidoreductase, molybdopterin-binding; COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | Hypothetical protein; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S- [...] | 0.710 |
| EAQ07143.1 | EAQ05538.1 | SKA53_02066 | SKA53_00589 | Iron-sulfur cluster-binding protein; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. | Oxidoreductase, molybdopterin-binding; COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | 0.625 |
| EAQ07143.1 | EAQ07263.1 | SKA53_02066 | SKA53_02666 | Iron-sulfur cluster-binding protein; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. | Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. | 0.553 |
| EAQ07143.1 | EAQ07264.1 | SKA53_02066 | SKA53_02671 | Iron-sulfur cluster-binding protein; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. | COG0155 Sulfite reductase, beta subunit (hemoprotein). | 0.635 |
| EAQ07143.1 | EAQ07315.1 | SKA53_02066 | SKA53_02926 | Iron-sulfur cluster-binding protein; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. | COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits. | 0.984 |
| EAQ07143.1 | EAQ07878.1 | SKA53_02066 | SKA53_09149 | Iron-sulfur cluster-binding protein; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. | COG1145 Ferredoxin. | 0.918 |
| EAQ07143.1 | cysC | SKA53_02066 | SKA53_08711 | Iron-sulfur cluster-binding protein; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. | Binfunctional sulfate adenylyltransferase subunit 1/adenylylsulfate kinase protein; Catalyzes the synthesis of activated sulfate. | 0.928 |
| EAQ07143.1 | cysQ | SKA53_02066 | SKA53_11603 | Iron-sulfur cluster-binding protein; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. | 3'-Phosphadenosine 5'-phosphosulfate 3'-phosphatase; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family. | 0.472 |
| EAQ07143.1 | msrP | SKA53_02066 | SKA53_10359 | Iron-sulfur cluster-binding protein; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. | Hypothetical protein; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S- [...] | 0.549 |
| EAQ07263.1 | EAQ05538.1 | SKA53_02666 | SKA53_00589 | Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. | Oxidoreductase, molybdopterin-binding; COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | 0.831 |
| EAQ07263.1 | EAQ07143.1 | SKA53_02666 | SKA53_02066 | Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. | Iron-sulfur cluster-binding protein; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. | 0.553 |
| EAQ07263.1 | EAQ07264.1 | SKA53_02666 | SKA53_02671 | Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. | COG0155 Sulfite reductase, beta subunit (hemoprotein). | 0.999 |
| EAQ07263.1 | EAQ07266.1 | SKA53_02666 | SKA53_02681 | Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. | Siroheme synthetase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | 0.995 |
| EAQ07263.1 | EAQ07315.1 | SKA53_02666 | SKA53_02926 | Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. | COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits. | 0.761 |
