| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAQ05231.1 | EAQ05467.1 | SKA53_05630 | SKA53_03624 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | COG2124 Cytochrome P450. | 0.543 |
| EAQ05231.1 | EAQ06946.1 | SKA53_05630 | SKA53_15401 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | Probable 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.511 |
| EAQ05231.1 | EAQ07715.1 | SKA53_05630 | SKA53_12798 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | Mannose-6-phosphate isomerase /; COG0836 Mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family. | 0.486 |
| EAQ05231.1 | EAQ07850.1 | SKA53_05630 | SKA53_09009 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | Hypothetical protein; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | 0.554 |
| EAQ05231.1 | EAQ07916.1 | SKA53_05630 | SKA53_09339 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase /3-hydroxybutyryl-CoA epimerase; COG1024 Enoyl-CoA hydratase/carnithine racemase. | 0.813 |
| EAQ05231.1 | EAQ08212.1 | SKA53_05630 | SKA53_10819 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | Glutamine-pyruvate aminotransferase; COG0067 Glutamate synthase domain 1. | 0.889 |
| EAQ05231.1 | lcdH | SKA53_05630 | SKA53_00914 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 3-hydroxybutyryl-CoA dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of L-carnitine to 3- dehydrocarnitine. | 0.676 |
| EAQ05231.1 | leuA | SKA53_05630 | SKA53_09014 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.853 |
| EAQ05467.1 | EAQ05231.1 | SKA53_03624 | SKA53_05630 | COG2124 Cytochrome P450. | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 0.543 |
| EAQ05467.1 | EAQ06946.1 | SKA53_03624 | SKA53_15401 | COG2124 Cytochrome P450. | Probable 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.788 |
| EAQ05467.1 | EAQ06947.1 | SKA53_03624 | SKA53_15406 | COG2124 Cytochrome P450. | Ferredoxin; COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1. | 0.940 |
| EAQ05467.1 | EAQ07850.1 | SKA53_03624 | SKA53_09009 | COG2124 Cytochrome P450. | Hypothetical protein; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | 0.833 |
| EAQ05467.1 | EAQ07916.1 | SKA53_03624 | SKA53_09339 | COG2124 Cytochrome P450. | enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase /3-hydroxybutyryl-CoA epimerase; COG1024 Enoyl-CoA hydratase/carnithine racemase. | 0.820 |
| EAQ05467.1 | EAQ08212.1 | SKA53_03624 | SKA53_10819 | COG2124 Cytochrome P450. | Glutamine-pyruvate aminotransferase; COG0067 Glutamate synthase domain 1. | 0.416 |
| EAQ05467.1 | lcdH | SKA53_03624 | SKA53_00914 | COG2124 Cytochrome P450. | 3-hydroxybutyryl-CoA dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of L-carnitine to 3- dehydrocarnitine. | 0.574 |
| EAQ06946.1 | EAQ05231.1 | SKA53_15401 | SKA53_05630 | Probable 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 0.511 |
| EAQ06946.1 | EAQ05467.1 | SKA53_15401 | SKA53_03624 | Probable 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | COG2124 Cytochrome P450. | 0.788 |
| EAQ06946.1 | EAQ06947.1 | SKA53_15401 | SKA53_15406 | Probable 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Ferredoxin; COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1. | 0.784 |
| EAQ06946.1 | EAQ07715.1 | SKA53_15401 | SKA53_12798 | Probable 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Mannose-6-phosphate isomerase /; COG0836 Mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family. | 0.773 |
| EAQ06946.1 | EAQ07850.1 | SKA53_15401 | SKA53_09009 | Probable 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Hypothetical protein; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | 0.466 |