| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAQ05967.1 | EAQ06479.1 | SKA53_07676 | SKA53_05308 | Putative Maf-like protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | mazG family protein; COG1694 Predicted pyrophosphatase. | 0.826 |
| EAQ05967.1 | EAQ07461.1 | SKA53_07676 | SKA53_11528 | Putative Maf-like protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | Putative S-adenosyl L-homocystein hydrolase; COG1896 Predicted hydrolases of HD superfamily. | 0.815 |
| EAQ05967.1 | EAQ07905.1 | SKA53_07676 | SKA53_09284 | Putative Maf-like protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family. | 0.815 |
| EAQ05967.1 | surE | SKA53_07676 | SKA53_02561 | Putative Maf-like protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | Survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.815 |
| EAQ05967.1 | tdk | SKA53_07676 | SKA53_09609 | Putative Maf-like protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | COG1435 Thymidine kinase. | 0.815 |
| EAQ05967.1 | thyX | SKA53_07676 | SKA53_07631 | Putative Maf-like protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. | 0.841 |
| EAQ05967.1 | tmk | SKA53_07676 | SKA53_06572 | Putative Maf-like protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.819 |
| EAQ06479.1 | EAQ05967.1 | SKA53_05308 | SKA53_07676 | mazG family protein; COG1694 Predicted pyrophosphatase. | Putative Maf-like protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | 0.826 |
| EAQ06479.1 | EAQ07461.1 | SKA53_05308 | SKA53_11528 | mazG family protein; COG1694 Predicted pyrophosphatase. | Putative S-adenosyl L-homocystein hydrolase; COG1896 Predicted hydrolases of HD superfamily. | 0.815 |
| EAQ06479.1 | EAQ07905.1 | SKA53_05308 | SKA53_09284 | mazG family protein; COG1694 Predicted pyrophosphatase. | COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family. | 0.815 |
| EAQ06479.1 | dut | SKA53_05308 | SKA53_14786 | mazG family protein; COG1694 Predicted pyrophosphatase. | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.552 |
| EAQ06479.1 | surE | SKA53_05308 | SKA53_02561 | mazG family protein; COG1694 Predicted pyrophosphatase. | Survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.818 |
| EAQ06479.1 | tdk | SKA53_05308 | SKA53_09609 | mazG family protein; COG1694 Predicted pyrophosphatase. | COG1435 Thymidine kinase. | 0.815 |
| EAQ06479.1 | thyX | SKA53_05308 | SKA53_07631 | mazG family protein; COG1694 Predicted pyrophosphatase. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. | 0.887 |
| EAQ06479.1 | tmk | SKA53_05308 | SKA53_06572 | mazG family protein; COG1694 Predicted pyrophosphatase. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.854 |
| EAQ07461.1 | EAQ05967.1 | SKA53_11528 | SKA53_07676 | Putative S-adenosyl L-homocystein hydrolase; COG1896 Predicted hydrolases of HD superfamily. | Putative Maf-like protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | 0.815 |
| EAQ07461.1 | EAQ06479.1 | SKA53_11528 | SKA53_05308 | Putative S-adenosyl L-homocystein hydrolase; COG1896 Predicted hydrolases of HD superfamily. | mazG family protein; COG1694 Predicted pyrophosphatase. | 0.815 |
| EAQ07461.1 | EAQ07905.1 | SKA53_11528 | SKA53_09284 | Putative S-adenosyl L-homocystein hydrolase; COG1896 Predicted hydrolases of HD superfamily. | COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family. | 0.815 |
| EAQ07461.1 | EAQ07924.1 | SKA53_11528 | SKA53_09379 | Putative S-adenosyl L-homocystein hydrolase; COG1896 Predicted hydrolases of HD superfamily. | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | 0.815 |
| EAQ07461.1 | deoA | SKA53_11528 | SKA53_09374 | Putative S-adenosyl L-homocystein hydrolase; COG1896 Predicted hydrolases of HD superfamily. | Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. | 0.820 |