| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAQ06607.1 | EAQ06637.1 | SKA53_13706 | SKA53_13856 | COG0842 ABC-type multidrug transport system, permease component. | CAAX amino terminal protease family protein; COG1266 Predicted metal-dependent membrane protease. | 0.542 |
| EAQ06607.1 | EAQ07950.1 | SKA53_13706 | SKA53_09509 | COG0842 ABC-type multidrug transport system, permease component. | COG0842 ABC-type multidrug transport system, permease component. | 0.448 |
| EAQ06607.1 | EAQ07987.1 | SKA53_13706 | SKA53_09694 | COG0842 ABC-type multidrug transport system, permease component. | Twin-arginine translocation pathway signal sequence domain protein; COG2217 Cation transport ATPase. | 0.593 |
| EAQ06637.1 | EAQ06607.1 | SKA53_13856 | SKA53_13706 | CAAX amino terminal protease family protein; COG1266 Predicted metal-dependent membrane protease. | COG0842 ABC-type multidrug transport system, permease component. | 0.542 |
| EAQ06637.1 | EAQ07950.1 | SKA53_13856 | SKA53_09509 | CAAX amino terminal protease family protein; COG1266 Predicted metal-dependent membrane protease. | COG0842 ABC-type multidrug transport system, permease component. | 0.542 |
| EAQ06637.1 | EAQ07987.1 | SKA53_13856 | SKA53_09694 | CAAX amino terminal protease family protein; COG1266 Predicted metal-dependent membrane protease. | Twin-arginine translocation pathway signal sequence domain protein; COG2217 Cation transport ATPase. | 0.533 |
| EAQ07266.1 | EAQ07987.1 | SKA53_02681 | SKA53_09694 | Siroheme synthetase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | Twin-arginine translocation pathway signal sequence domain protein; COG2217 Cation transport ATPase. | 0.877 |
| EAQ07266.1 | EAQ08049.1 | SKA53_02681 | SKA53_10004 | Siroheme synthetase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | Precorrin-3B C17-methyltransferase region; COG2073 Cobalamin biosynthesis protein CbiG. | 0.971 |
| EAQ07266.1 | EAQ08051.1 | SKA53_02681 | SKA53_10014 | Siroheme synthetase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | CobL, precorrin-6Y C5,15-methyltransferase; COG2241 Precorrin-6B methylase 1. | 0.967 |
| EAQ07266.1 | EAQ08212.1 | SKA53_02681 | SKA53_10819 | Siroheme synthetase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | Glutamine-pyruvate aminotransferase; COG0067 Glutamate synthase domain 1. | 0.582 |
| EAQ07266.1 | ribB | SKA53_02681 | SKA53_01971 | Siroheme synthetase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | Bifunctional GTP cyclohydrolaseII/3,4-dihydroxy-2butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.429 |
| EAQ07950.1 | EAQ06607.1 | SKA53_09509 | SKA53_13706 | COG0842 ABC-type multidrug transport system, permease component. | COG0842 ABC-type multidrug transport system, permease component. | 0.448 |
| EAQ07950.1 | EAQ06637.1 | SKA53_09509 | SKA53_13856 | COG0842 ABC-type multidrug transport system, permease component. | CAAX amino terminal protease family protein; COG1266 Predicted metal-dependent membrane protease. | 0.542 |
| EAQ07950.1 | EAQ07987.1 | SKA53_09509 | SKA53_09694 | COG0842 ABC-type multidrug transport system, permease component. | Twin-arginine translocation pathway signal sequence domain protein; COG2217 Cation transport ATPase. | 0.593 |
| EAQ07986.1 | EAQ07987.1 | SKA53_09689 | SKA53_09694 | Transcriptional regulators, LysR family; COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family. | Twin-arginine translocation pathway signal sequence domain protein; COG2217 Cation transport ATPase. | 0.528 |
| EAQ07986.1 | EAQ07988.1 | SKA53_09689 | SKA53_09699 | Transcriptional regulators, LysR family; COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family. | Transcriptional regulator, MarR family; COG1846 Transcriptional regulators. | 0.530 |
| EAQ07986.1 | EAQ08212.1 | SKA53_09689 | SKA53_10819 | Transcriptional regulators, LysR family; COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family. | Glutamine-pyruvate aminotransferase; COG0067 Glutamate synthase domain 1. | 0.536 |
| EAQ07987.1 | EAQ06607.1 | SKA53_09694 | SKA53_13706 | Twin-arginine translocation pathway signal sequence domain protein; COG2217 Cation transport ATPase. | COG0842 ABC-type multidrug transport system, permease component. | 0.593 |
| EAQ07987.1 | EAQ06637.1 | SKA53_09694 | SKA53_13856 | Twin-arginine translocation pathway signal sequence domain protein; COG2217 Cation transport ATPase. | CAAX amino terminal protease family protein; COG1266 Predicted metal-dependent membrane protease. | 0.533 |
| EAQ07987.1 | EAQ07266.1 | SKA53_09694 | SKA53_02681 | Twin-arginine translocation pathway signal sequence domain protein; COG2217 Cation transport ATPase. | Siroheme synthetase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | 0.877 |