| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAQ05630.1 | EAQ07998.1 | SKA53_01049 | SKA53_09749 | Mandelate racemase/muconate lactonizing enzyme family protein; COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily; Belongs to the mandelate racemase/muconate lactonizing enzyme family. | 2-dehydropantoate 2-reductase; COG1893 Ketopantoate reductase. | 0.521 |
| EAQ05758.1 | EAQ07119.1 | SKA53_06627 | SKA53_01946 | Hypothetical protein; COG1082 Sugar phosphate isomerases/epimerases. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.404 |
| EAQ05758.1 | EAQ07998.1 | SKA53_06627 | SKA53_09749 | Hypothetical protein; COG1082 Sugar phosphate isomerases/epimerases. | 2-dehydropantoate 2-reductase; COG1893 Ketopantoate reductase. | 0.504 |
| EAQ05758.1 | EAQ07999.1 | SKA53_06627 | SKA53_09754 | Hypothetical protein; COG1082 Sugar phosphate isomerases/epimerases. | COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II. | 0.615 |
| EAQ05758.1 | nadE | SKA53_06627 | SKA53_08994 | Hypothetical protein; COG1082 Sugar phosphate isomerases/epimerases. | NAD(+) synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.768 |
| EAQ07119.1 | EAQ05758.1 | SKA53_01946 | SKA53_06627 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Hypothetical protein; COG1082 Sugar phosphate isomerases/epimerases. | 0.404 |
| EAQ07119.1 | EAQ07200.1 | SKA53_01946 | SKA53_02351 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | COG0413 Ketopantoate hydroxymethyltransferase. | 0.674 |
| EAQ07119.1 | EAQ07769.1 | SKA53_01946 | SKA53_13068 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase. | 0.737 |
| EAQ07119.1 | EAQ07998.1 | SKA53_01946 | SKA53_09749 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 2-dehydropantoate 2-reductase; COG1893 Ketopantoate reductase. | 0.426 |
| EAQ07119.1 | nadE | SKA53_01946 | SKA53_08994 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | NAD(+) synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.795 |
| EAQ07200.1 | EAQ07119.1 | SKA53_02351 | SKA53_01946 | COG0413 Ketopantoate hydroxymethyltransferase. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.674 |
| EAQ07200.1 | EAQ07769.1 | SKA53_02351 | SKA53_13068 | COG0413 Ketopantoate hydroxymethyltransferase. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase. | 0.536 |
| EAQ07200.1 | EAQ07998.1 | SKA53_02351 | SKA53_09749 | COG0413 Ketopantoate hydroxymethyltransferase. | 2-dehydropantoate 2-reductase; COG1893 Ketopantoate reductase. | 0.957 |
| EAQ07769.1 | EAQ07119.1 | SKA53_13068 | SKA53_01946 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.737 |
| EAQ07769.1 | EAQ07200.1 | SKA53_13068 | SKA53_02351 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase. | COG0413 Ketopantoate hydroxymethyltransferase. | 0.536 |
| EAQ07769.1 | EAQ07998.1 | SKA53_13068 | SKA53_09749 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase. | 2-dehydropantoate 2-reductase; COG1893 Ketopantoate reductase. | 0.568 |
| EAQ07769.1 | nadE | SKA53_13068 | SKA53_08994 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase. | NAD(+) synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.540 |
| EAQ07998.1 | EAQ05630.1 | SKA53_09749 | SKA53_01049 | 2-dehydropantoate 2-reductase; COG1893 Ketopantoate reductase. | Mandelate racemase/muconate lactonizing enzyme family protein; COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily; Belongs to the mandelate racemase/muconate lactonizing enzyme family. | 0.521 |
| EAQ07998.1 | EAQ05758.1 | SKA53_09749 | SKA53_06627 | 2-dehydropantoate 2-reductase; COG1893 Ketopantoate reductase. | Hypothetical protein; COG1082 Sugar phosphate isomerases/epimerases. | 0.504 |
| EAQ07998.1 | EAQ07119.1 | SKA53_09749 | SKA53_01946 | 2-dehydropantoate 2-reductase; COG1893 Ketopantoate reductase. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.426 |