| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAQ06820.1 | EAQ08058.1 | SKA53_14771 | SKA53_10049 | Possible adenosyl cobinamide kinase/ cobinamide phosphateguanylyltransferase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | Cobalamin biosynthetic protein CobC; COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase. | 0.954 |
| EAQ06820.1 | EAQ08067.1 | SKA53_14771 | SKA53_10094 | Possible adenosyl cobinamide kinase/ cobinamide phosphateguanylyltransferase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | cob(I)yrinic acid a,c-diamide adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | 0.977 |
| EAQ06820.1 | cobD | SKA53_14771 | SKA53_10054 | Possible adenosyl cobinamide kinase/ cobinamide phosphateguanylyltransferase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.989 |
| EAQ06820.1 | cobQ | SKA53_14771 | SKA53_15271 | Possible adenosyl cobinamide kinase/ cobinamide phosphateguanylyltransferase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.995 |
| EAQ06820.1 | cobT | SKA53_14771 | SKA53_07431 | Possible adenosyl cobinamide kinase/ cobinamide phosphateguanylyltransferase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | Nicotinate-nucleotide-- dimethylbenzimidazolephosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). | 0.995 |
| EAQ08057.1 | EAQ08058.1 | SKA53_10044 | SKA53_10049 | COG5469 Predicted metal-binding protein. | Cobalamin biosynthetic protein CobC; COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase. | 0.872 |
| EAQ08057.1 | cobD | SKA53_10044 | SKA53_10054 | COG5469 Predicted metal-binding protein. | Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.853 |
| EAQ08058.1 | EAQ06820.1 | SKA53_10049 | SKA53_14771 | Cobalamin biosynthetic protein CobC; COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase. | Possible adenosyl cobinamide kinase/ cobinamide phosphateguanylyltransferase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | 0.954 |
| EAQ08058.1 | EAQ08057.1 | SKA53_10049 | SKA53_10044 | Cobalamin biosynthetic protein CobC; COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase. | COG5469 Predicted metal-binding protein. | 0.872 |
| EAQ08058.1 | EAQ08067.1 | SKA53_10049 | SKA53_10094 | Cobalamin biosynthetic protein CobC; COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase. | cob(I)yrinic acid a,c-diamide adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | 0.930 |
| EAQ08058.1 | cobD | SKA53_10049 | SKA53_10054 | Cobalamin biosynthetic protein CobC; COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase. | Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.994 |
| EAQ08058.1 | cobQ | SKA53_10049 | SKA53_15271 | Cobalamin biosynthetic protein CobC; COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase. | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.964 |
| EAQ08058.1 | cobT | SKA53_10049 | SKA53_07431 | Cobalamin biosynthetic protein CobC; COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase. | Nicotinate-nucleotide-- dimethylbenzimidazolephosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). | 0.927 |
| EAQ08058.1 | hisB | SKA53_10049 | SKA53_07361 | Cobalamin biosynthetic protein CobC; COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase. | COG0131 Imidazoleglycerol-phosphate dehydratase. | 0.898 |
| EAQ08058.1 | hisD | SKA53_10049 | SKA53_07656 | Cobalamin biosynthetic protein CobC; COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase. | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | 0.896 |
| EAQ08058.1 | hisF | SKA53_10049 | SKA53_07386 | Cobalamin biosynthetic protein CobC; COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase. | Imidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | 0.893 |
| EAQ08058.1 | hisH | SKA53_10049 | SKA53_07366 | Cobalamin biosynthetic protein CobC; COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase. | Imidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | 0.903 |
| EAQ08067.1 | EAQ06820.1 | SKA53_10094 | SKA53_14771 | cob(I)yrinic acid a,c-diamide adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | Possible adenosyl cobinamide kinase/ cobinamide phosphateguanylyltransferase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | 0.977 |
| EAQ08067.1 | EAQ08058.1 | SKA53_10094 | SKA53_10049 | cob(I)yrinic acid a,c-diamide adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | Cobalamin biosynthetic protein CobC; COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase. | 0.930 |
| EAQ08067.1 | cobD | SKA53_10094 | SKA53_10054 | cob(I)yrinic acid a,c-diamide adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.972 |