| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAQ06820.1 | EAQ08048.1 | SKA53_14771 | SKA53_09999 | Possible adenosyl cobinamide kinase/ cobinamide phosphateguanylyltransferase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | COG2875 Precorrin-4 methylase. | 0.888 |
| EAQ06820.1 | EAQ08049.1 | SKA53_14771 | SKA53_10004 | Possible adenosyl cobinamide kinase/ cobinamide phosphateguanylyltransferase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | Precorrin-3B C17-methyltransferase region; COG2073 Cobalamin biosynthesis protein CbiG. | 0.954 |
| EAQ06820.1 | EAQ08052.1 | SKA53_14771 | SKA53_10019 | Possible adenosyl cobinamide kinase/ cobinamide phosphateguanylyltransferase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | precorrin-8X methylmutase; COG2082 Precorrin isomerase. | 0.636 |
| EAQ06820.1 | EAQ08058.1 | SKA53_14771 | SKA53_10049 | Possible adenosyl cobinamide kinase/ cobinamide phosphateguanylyltransferase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | Cobalamin biosynthetic protein CobC; COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase. | 0.957 |
| EAQ06820.1 | EAQ08067.1 | SKA53_14771 | SKA53_10094 | Possible adenosyl cobinamide kinase/ cobinamide phosphateguanylyltransferase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | cob(I)yrinic acid a,c-diamide adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | 0.978 |
| EAQ06820.1 | cobB | SKA53_14771 | SKA53_03151 | Possible adenosyl cobinamide kinase/ cobinamide phosphateguanylyltransferase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.931 |
| EAQ06820.1 | cobD | SKA53_14771 | SKA53_10054 | Possible adenosyl cobinamide kinase/ cobinamide phosphateguanylyltransferase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.995 |
| EAQ06820.1 | cobQ | SKA53_14771 | SKA53_15271 | Possible adenosyl cobinamide kinase/ cobinamide phosphateguanylyltransferase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.992 |
| EAQ06820.1 | cobS | SKA53_14771 | SKA53_07436 | Possible adenosyl cobinamide kinase/ cobinamide phosphateguanylyltransferase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | Putative Cobalamin (5'-phosphate) synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.993 |
| EAQ06820.1 | cobT | SKA53_14771 | SKA53_07431 | Possible adenosyl cobinamide kinase/ cobinamide phosphateguanylyltransferase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | Nicotinate-nucleotide-- dimethylbenzimidazolephosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). | 0.995 |
| EAQ08048.1 | EAQ06820.1 | SKA53_09999 | SKA53_14771 | COG2875 Precorrin-4 methylase. | Possible adenosyl cobinamide kinase/ cobinamide phosphateguanylyltransferase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | 0.888 |
| EAQ08048.1 | EAQ08049.1 | SKA53_09999 | SKA53_10004 | COG2875 Precorrin-4 methylase. | Precorrin-3B C17-methyltransferase region; COG2073 Cobalamin biosynthesis protein CbiG. | 0.999 |
| EAQ08048.1 | EAQ08052.1 | SKA53_09999 | SKA53_10019 | COG2875 Precorrin-4 methylase. | precorrin-8X methylmutase; COG2082 Precorrin isomerase. | 0.996 |
| EAQ08048.1 | EAQ08067.1 | SKA53_09999 | SKA53_10094 | COG2875 Precorrin-4 methylase. | cob(I)yrinic acid a,c-diamide adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | 0.747 |
| EAQ08048.1 | cobB | SKA53_09999 | SKA53_03151 | COG2875 Precorrin-4 methylase. | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.934 |
| EAQ08048.1 | cobD | SKA53_09999 | SKA53_10054 | COG2875 Precorrin-4 methylase. | Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.897 |
| EAQ08048.1 | cobQ | SKA53_09999 | SKA53_15271 | COG2875 Precorrin-4 methylase. | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.969 |
| EAQ08048.1 | cobS | SKA53_09999 | SKA53_07436 | COG2875 Precorrin-4 methylase. | Putative Cobalamin (5'-phosphate) synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.850 |
| EAQ08048.1 | cobT | SKA53_09999 | SKA53_07431 | COG2875 Precorrin-4 methylase. | Nicotinate-nucleotide-- dimethylbenzimidazolephosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). | 0.659 |
| EAQ08049.1 | EAQ06820.1 | SKA53_10004 | SKA53_14771 | Precorrin-3B C17-methyltransferase region; COG2073 Cobalamin biosynthesis protein CbiG. | Possible adenosyl cobinamide kinase/ cobinamide phosphateguanylyltransferase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | 0.954 |