Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
smcSMC protein; Required for chromosome condensation and partitioning. Belongs to the SMC family. (1151 aa)    
Predicted Functional Partners:
EAQ06497.1
Segregation and condensation protein A; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.
 
 
 0.951
EAQ06061.1
Hypothetical protein; COG0642 Signal transduction histidine kinase.
   
 0.858
EAQ06496.1
Segregation and condensation protein B; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.
 
 
 
 0.832
EAQ06346.1
Methyl-accepting chemotaxis protein McpD; COG2202 FOG: PAS/PAC domain.
  
 
  0.766
EAQ06517.1
COG0840 Methyl-accepting chemotaxis protein.
    
  0.748
EAQ06858.1
Hypothetical protein; COG0840 Methyl-accepting chemotaxis protein.
    
  0.748
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
 
 0.737
EAQ06345.1
Hypothetical protein; COG0840 Methyl-accepting chemotaxis protein.
    
  0.731
EAQ07462.1
Sensory box-containing diguanylate cyclase, putative; COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain.
     
 0.711
EAQ07807.1
Hypothetical protein; COG2199 FOG: GGDEF domain.
     
 0.711
Your Current Organism:
Yoonia vestfoldensis SKA53
NCBI taxonomy Id: 314232
Other names: Loktanella vestfoldensis SKA53, Y. vestfoldensis SKA53
Server load: low (14%) [HD]