| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAQ05211.1 | EAQ05427.1 | SKA53_03309 | SKA53_03424 | Hypothetical protein; COG1410 Methionine synthase I, cobalamin-binding domain. | COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain. | 0.998 |
| EAQ05211.1 | EAQ05916.1 | SKA53_03309 | SKA53_07421 | Hypothetical protein; COG1410 Methionine synthase I, cobalamin-binding domain. | COG2873 O-acetylhomoserine sulfhydrylase. | 0.880 |
| EAQ05211.1 | EAQ06946.1 | SKA53_03309 | SKA53_15401 | Hypothetical protein; COG1410 Methionine synthase I, cobalamin-binding domain. | Probable 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.922 |
| EAQ05211.1 | EAQ08080.1 | SKA53_03309 | SKA53_10159 | Hypothetical protein; COG1410 Methionine synthase I, cobalamin-binding domain. | FAD dependent oxidoreductase/aminomethyl transferase; COG0665 Glycine/D-amino acid oxidases (deaminating); Belongs to the GcvT family. | 0.618 |
| EAQ05211.1 | EAQ08081.1 | SKA53_03309 | SKA53_10164 | Hypothetical protein; COG1410 Methionine synthase I, cobalamin-binding domain. | Homocysteine S-methyltransferase family protein; COG2040 Homocysteine/selenocysteine methylase (S-methylmethionine-dependent). | 0.791 |
| EAQ05211.1 | EAQ08082.1 | SKA53_03309 | SKA53_10169 | Hypothetical protein; COG1410 Methionine synthase I, cobalamin-binding domain. | Aminomethyl transferase family protein; COG0665 Glycine/D-amino acid oxidases (deaminating); Belongs to the GcvT family. | 0.643 |
| EAQ05211.1 | metK | SKA53_03309 | SKA53_01171 | Hypothetical protein; COG1410 Methionine synthase I, cobalamin-binding domain. | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.885 |
| EAQ05427.1 | EAQ05211.1 | SKA53_03424 | SKA53_03309 | COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain. | Hypothetical protein; COG1410 Methionine synthase I, cobalamin-binding domain. | 0.998 |
| EAQ05427.1 | EAQ05916.1 | SKA53_03424 | SKA53_07421 | COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain. | COG2873 O-acetylhomoserine sulfhydrylase. | 0.937 |
| EAQ05427.1 | EAQ06946.1 | SKA53_03424 | SKA53_15401 | COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain. | Probable 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.926 |
| EAQ05427.1 | EAQ08080.1 | SKA53_03424 | SKA53_10159 | COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain. | FAD dependent oxidoreductase/aminomethyl transferase; COG0665 Glycine/D-amino acid oxidases (deaminating); Belongs to the GcvT family. | 0.673 |
| EAQ05427.1 | EAQ08081.1 | SKA53_03424 | SKA53_10164 | COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain. | Homocysteine S-methyltransferase family protein; COG2040 Homocysteine/selenocysteine methylase (S-methylmethionine-dependent). | 0.735 |
| EAQ05427.1 | EAQ08082.1 | SKA53_03424 | SKA53_10169 | COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain. | Aminomethyl transferase family protein; COG0665 Glycine/D-amino acid oxidases (deaminating); Belongs to the GcvT family. | 0.685 |
| EAQ05427.1 | metK | SKA53_03424 | SKA53_01171 | COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain. | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.939 |
| EAQ05916.1 | EAQ05211.1 | SKA53_07421 | SKA53_03309 | COG2873 O-acetylhomoserine sulfhydrylase. | Hypothetical protein; COG1410 Methionine synthase I, cobalamin-binding domain. | 0.880 |
| EAQ05916.1 | EAQ05427.1 | SKA53_07421 | SKA53_03424 | COG2873 O-acetylhomoserine sulfhydrylase. | COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain. | 0.937 |
| EAQ05916.1 | EAQ06946.1 | SKA53_07421 | SKA53_15401 | COG2873 O-acetylhomoserine sulfhydrylase. | Probable 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.964 |
| EAQ05916.1 | EAQ08081.1 | SKA53_07421 | SKA53_10164 | COG2873 O-acetylhomoserine sulfhydrylase. | Homocysteine S-methyltransferase family protein; COG2040 Homocysteine/selenocysteine methylase (S-methylmethionine-dependent). | 0.765 |
| EAQ06589.1 | EAQ06946.1 | SKA53_13616 | SKA53_15401 | COG2020 putative protein-S-isoprenylcysteine methyltransferase. | Probable 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.742 |
| EAQ06589.1 | EAQ08081.1 | SKA53_13616 | SKA53_10164 | COG2020 putative protein-S-isoprenylcysteine methyltransferase. | Homocysteine S-methyltransferase family protein; COG2040 Homocysteine/selenocysteine methylase (S-methylmethionine-dependent). | 0.635 |