Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
EAQ08085.1COG1956 GAF domain-containing protein. (150 aa)    
Predicted Functional Partners:
EAQ06744.1
COG1448 Aspartate/tyrosine/aromatic aminotransferase.
    
  0.830
EAQ05916.1
COG2873 O-acetylhomoserine sulfhydrylase.
    
  0.816
metK
S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
     
  0.815
EAQ05211.1
Hypothetical protein; COG1410 Methionine synthase I, cobalamin-binding domain.
     
  0.815
EAQ05427.1
COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain.
     
  0.815
EAQ06946.1
Probable 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
     
  0.815
metZ
O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide.
     
  0.727
EAQ08104.1
COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases.
     
  0.727
EAQ08081.1
Homocysteine S-methyltransferase family protein; COG2040 Homocysteine/selenocysteine methylase (S-methylmethionine-dependent).
    
  0.710
EAQ08084.1
DNA-binding protein, putative; COG1396 Predicted transcriptional regulators.
 
     0.681
Your Current Organism:
Yoonia vestfoldensis SKA53
NCBI taxonomy Id: 314232
Other names: Loktanella vestfoldensis SKA53, Y. vestfoldensis SKA53
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