| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAQ05642.1 | EAQ06857.1 | SKA53_06047 | SKA53_14956 | COG0513 Superfamily II DNA and RNA helicases; Belongs to the DEAD box helicase family. | DEAD/DEAH box helicase; COG0513 Superfamily II DNA and RNA helicases. | 0.752 |
| EAQ05642.1 | rnr | SKA53_06047 | SKA53_10249 | COG0513 Superfamily II DNA and RNA helicases; Belongs to the DEAD box helicase family. | Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. | 0.605 |
| EAQ05642.1 | rph | SKA53_06047 | SKA53_11843 | COG0513 Superfamily II DNA and RNA helicases; Belongs to the DEAD box helicase family. | Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | 0.763 |
| EAQ05642.1 | rppH | SKA53_06047 | SKA53_10254 | COG0513 Superfamily II DNA and RNA helicases; Belongs to the DEAD box helicase family. | Hydrolase, NUDIX family, NudH subfamily; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily. | 0.778 |
| EAQ05791.1 | EAQ07715.1 | SKA53_06792 | SKA53_12798 | Transcriptional regulator/arsenate reductase; COG0640 Predicted transcriptional regulators; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. | Mannose-6-phosphate isomerase /; COG0836 Mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family. | 0.680 |
| EAQ05791.1 | rppH | SKA53_06792 | SKA53_10254 | Transcriptional regulator/arsenate reductase; COG0640 Predicted transcriptional regulators; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. | Hydrolase, NUDIX family, NudH subfamily; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily. | 0.638 |
| EAQ06457.1 | rnr | SKA53_05198 | SKA53_10249 | DEAD-box protein, ATP-independent RNA helicase; COG0513 Superfamily II DNA and RNA helicases; Belongs to the DEAD box helicase family. | Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. | 0.406 |
| EAQ06457.1 | rph | SKA53_05198 | SKA53_11843 | DEAD-box protein, ATP-independent RNA helicase; COG0513 Superfamily II DNA and RNA helicases; Belongs to the DEAD box helicase family. | Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | 0.763 |
| EAQ06457.1 | rppH | SKA53_05198 | SKA53_10254 | DEAD-box protein, ATP-independent RNA helicase; COG0513 Superfamily II DNA and RNA helicases; Belongs to the DEAD box helicase family. | Hydrolase, NUDIX family, NudH subfamily; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily. | 0.778 |
| EAQ06857.1 | EAQ05642.1 | SKA53_14956 | SKA53_06047 | DEAD/DEAH box helicase; COG0513 Superfamily II DNA and RNA helicases. | COG0513 Superfamily II DNA and RNA helicases; Belongs to the DEAD box helicase family. | 0.752 |
| EAQ06857.1 | rnr | SKA53_14956 | SKA53_10249 | DEAD/DEAH box helicase; COG0513 Superfamily II DNA and RNA helicases. | Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. | 0.646 |
| EAQ06857.1 | rph | SKA53_14956 | SKA53_11843 | DEAD/DEAH box helicase; COG0513 Superfamily II DNA and RNA helicases. | Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | 0.763 |
| EAQ06857.1 | rppH | SKA53_14956 | SKA53_10254 | DEAD/DEAH box helicase; COG0513 Superfamily II DNA and RNA helicases. | Hydrolase, NUDIX family, NudH subfamily; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily. | 0.778 |
| EAQ07715.1 | EAQ05791.1 | SKA53_12798 | SKA53_06792 | Mannose-6-phosphate isomerase /; COG0836 Mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family. | Transcriptional regulator/arsenate reductase; COG0640 Predicted transcriptional regulators; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. | 0.680 |
| EAQ07715.1 | nadE | SKA53_12798 | SKA53_08994 | Mannose-6-phosphate isomerase /; COG0836 Mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family. | NAD(+) synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.600 |
| EAQ07715.1 | ribB | SKA53_12798 | SKA53_01971 | Mannose-6-phosphate isomerase /; COG0836 Mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family. | Bifunctional GTP cyclohydrolaseII/3,4-dihydroxy-2butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.494 |
| EAQ07715.1 | rppH | SKA53_12798 | SKA53_10254 | Mannose-6-phosphate isomerase /; COG0836 Mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family. | Hydrolase, NUDIX family, NudH subfamily; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily. | 0.778 |
| dapF | ribB | SKA53_12208 | SKA53_01971 | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | Bifunctional GTP cyclohydrolaseII/3,4-dihydroxy-2butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.546 |
| dapF | rppH | SKA53_12208 | SKA53_10254 | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | Hydrolase, NUDIX family, NudH subfamily; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily. | 0.955 |
| nadE | EAQ07715.1 | SKA53_08994 | SKA53_12798 | NAD(+) synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | Mannose-6-phosphate isomerase /; COG0836 Mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family. | 0.600 |