| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAQ07907.1 | EAQ08181.1 | SKA53_09294 | SKA53_10664 | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | Dihydropyrimidinase; COG0044 Dihydroorotase and related cyclic amidohydrolases. | 0.912 |
| EAQ07907.1 | EAQ08183.1 | SKA53_09294 | SKA53_10674 | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | N-carbamoyl-L-amino acid amidohydrolase; COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases. | 0.498 |
| EAQ07907.1 | EAQ08185.1 | SKA53_09294 | SKA53_10684 | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | COG0167 Dihydroorotate dehydrogenase. | 0.863 |
| EAQ07907.1 | EAQ08186.1 | SKA53_09294 | SKA53_10689 | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | Pyridine nucleotide-disulphide oxidoreductase family protein; COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases. | 0.583 |
| EAQ07907.1 | carA | SKA53_09294 | SKA53_07007 | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | COG0505 Carbamoylphosphate synthase small subunit; Belongs to the CarA family. | 0.937 |
| EAQ07907.1 | carB | SKA53_09294 | SKA53_09594 | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); Belongs to the CarB family. | 0.964 |
| EAQ07907.1 | pyrB | SKA53_09294 | SKA53_14296 | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | COG0540 Aspartate carbamoyltransferase, catalytic chain; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.944 |
| EAQ07907.1 | pyrE | SKA53_09294 | SKA53_02601 | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.993 |
| EAQ08177.1 | EAQ08180.1 | SKA53_10644 | SKA53_10659 | ABC transporter, periplasmic substrate-binding protein; COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components. | ABC transporter, ATP-binding protein; COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component. | 0.957 |
| EAQ08177.1 | EAQ08181.1 | SKA53_10644 | SKA53_10664 | ABC transporter, periplasmic substrate-binding protein; COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components. | Dihydropyrimidinase; COG0044 Dihydroorotase and related cyclic amidohydrolases. | 0.832 |
| EAQ08177.1 | EAQ08183.1 | SKA53_10644 | SKA53_10674 | ABC transporter, periplasmic substrate-binding protein; COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components. | N-carbamoyl-L-amino acid amidohydrolase; COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases. | 0.675 |
| EAQ08177.1 | EAQ08185.1 | SKA53_10644 | SKA53_10684 | ABC transporter, periplasmic substrate-binding protein; COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components. | COG0167 Dihydroorotate dehydrogenase. | 0.667 |
| EAQ08177.1 | EAQ08186.1 | SKA53_10644 | SKA53_10689 | ABC transporter, periplasmic substrate-binding protein; COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components. | Pyridine nucleotide-disulphide oxidoreductase family protein; COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases. | 0.510 |
| EAQ08180.1 | EAQ08177.1 | SKA53_10659 | SKA53_10644 | ABC transporter, ATP-binding protein; COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component. | ABC transporter, periplasmic substrate-binding protein; COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components. | 0.957 |
| EAQ08180.1 | EAQ08181.1 | SKA53_10659 | SKA53_10664 | ABC transporter, ATP-binding protein; COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component. | Dihydropyrimidinase; COG0044 Dihydroorotase and related cyclic amidohydrolases. | 0.883 |
| EAQ08180.1 | EAQ08183.1 | SKA53_10659 | SKA53_10674 | ABC transporter, ATP-binding protein; COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component. | N-carbamoyl-L-amino acid amidohydrolase; COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases. | 0.591 |
| EAQ08180.1 | EAQ08185.1 | SKA53_10659 | SKA53_10684 | ABC transporter, ATP-binding protein; COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component. | COG0167 Dihydroorotate dehydrogenase. | 0.664 |
| EAQ08180.1 | EAQ08186.1 | SKA53_10659 | SKA53_10689 | ABC transporter, ATP-binding protein; COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component. | Pyridine nucleotide-disulphide oxidoreductase family protein; COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases. | 0.491 |
| EAQ08181.1 | EAQ07907.1 | SKA53_10664 | SKA53_09294 | Dihydropyrimidinase; COG0044 Dihydroorotase and related cyclic amidohydrolases. | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.912 |
| EAQ08181.1 | EAQ08177.1 | SKA53_10664 | SKA53_10644 | Dihydropyrimidinase; COG0044 Dihydroorotase and related cyclic amidohydrolases. | ABC transporter, periplasmic substrate-binding protein; COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components. | 0.832 |