| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAQ05301.1 | EAQ05302.1 | SKA53_05980 | SKA53_05985 | Sarcosine oxidase, alpha subunit family; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; Belongs to the GcvT family. | COG4311 Sarcosine oxidase delta subunit. | 0.997 |
| EAQ05301.1 | EAQ07113.1 | SKA53_05980 | SKA53_01916 | Sarcosine oxidase, alpha subunit family; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; Belongs to the GcvT family. | COG4311 Sarcosine oxidase delta subunit. | 0.990 |
| EAQ05301.1 | EAQ07114.1 | SKA53_05980 | SKA53_01921 | Sarcosine oxidase, alpha subunit family; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; Belongs to the GcvT family. | Sarcosine oxidase, alpha subunit family; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; Belongs to the GcvT family. | 0.463 |
| EAQ05301.1 | EAQ08212.1 | SKA53_05980 | SKA53_10819 | Sarcosine oxidase, alpha subunit family; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; Belongs to the GcvT family. | Glutamine-pyruvate aminotransferase; COG0067 Glutamate synthase domain 1. | 0.903 |
| EAQ05301.1 | EAQ08234.1 | SKA53_05980 | SKA53_10929 | Sarcosine oxidase, alpha subunit family; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; Belongs to the GcvT family. | COG4583 Sarcosine oxidase gamma subunit. | 0.958 |
| EAQ05301.1 | EAQ08235.1 | SKA53_05980 | SKA53_10934 | Sarcosine oxidase, alpha subunit family; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; Belongs to the GcvT family. | Sarcosine oxidase, alpha subunit; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; Belongs to the GcvT family. | 0.463 |
| EAQ05301.1 | EAQ08236.1 | SKA53_05980 | SKA53_10939 | Sarcosine oxidase, alpha subunit family; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; Belongs to the GcvT family. | Hypothetical protein; COG4311 Sarcosine oxidase delta subunit. | 0.990 |
| EAQ05301.1 | EAQ08237.1 | SKA53_05980 | SKA53_10944 | Sarcosine oxidase, alpha subunit family; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; Belongs to the GcvT family. | Hypothetical protein; COG0665 Glycine/D-amino acid oxidases (deaminating). | 0.963 |
| EAQ05301.1 | glyA-2 | SKA53_05980 | SKA53_10924 | Sarcosine oxidase, alpha subunit family; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; Belongs to the GcvT family. | Hypothetical protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.892 |
| EAQ05302.1 | EAQ05301.1 | SKA53_05985 | SKA53_05980 | COG4311 Sarcosine oxidase delta subunit. | Sarcosine oxidase, alpha subunit family; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; Belongs to the GcvT family. | 0.997 |
| EAQ05302.1 | EAQ07113.1 | SKA53_05985 | SKA53_01916 | COG4311 Sarcosine oxidase delta subunit. | COG4311 Sarcosine oxidase delta subunit. | 0.770 |
| EAQ05302.1 | EAQ07114.1 | SKA53_05985 | SKA53_01921 | COG4311 Sarcosine oxidase delta subunit. | Sarcosine oxidase, alpha subunit family; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; Belongs to the GcvT family. | 0.987 |
| EAQ05302.1 | EAQ08212.1 | SKA53_05985 | SKA53_10819 | COG4311 Sarcosine oxidase delta subunit. | Glutamine-pyruvate aminotransferase; COG0067 Glutamate synthase domain 1. | 0.883 |
| EAQ05302.1 | EAQ08234.1 | SKA53_05985 | SKA53_10929 | COG4311 Sarcosine oxidase delta subunit. | COG4583 Sarcosine oxidase gamma subunit. | 0.952 |
| EAQ05302.1 | EAQ08235.1 | SKA53_05985 | SKA53_10934 | COG4311 Sarcosine oxidase delta subunit. | Sarcosine oxidase, alpha subunit; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; Belongs to the GcvT family. | 0.987 |
| EAQ05302.1 | EAQ08237.1 | SKA53_05985 | SKA53_10944 | COG4311 Sarcosine oxidase delta subunit. | Hypothetical protein; COG0665 Glycine/D-amino acid oxidases (deaminating). | 0.896 |
| EAQ05302.1 | glyA-2 | SKA53_05985 | SKA53_10924 | COG4311 Sarcosine oxidase delta subunit. | Hypothetical protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.562 |
| EAQ07113.1 | EAQ05301.1 | SKA53_01916 | SKA53_05980 | COG4311 Sarcosine oxidase delta subunit. | Sarcosine oxidase, alpha subunit family; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; Belongs to the GcvT family. | 0.990 |
| EAQ07113.1 | EAQ05302.1 | SKA53_01916 | SKA53_05985 | COG4311 Sarcosine oxidase delta subunit. | COG4311 Sarcosine oxidase delta subunit. | 0.770 |
| EAQ07113.1 | EAQ07114.1 | SKA53_01916 | SKA53_01921 | COG4311 Sarcosine oxidase delta subunit. | Sarcosine oxidase, alpha subunit family; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; Belongs to the GcvT family. | 0.997 |