| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAQ05838.1 | EAQ06398.1 | SKA53_07027 | SKA53_04903 | COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases. | Aromatic-rich family protein; COG2867 Oligoketide cyclase/lipid transport protein. | 0.408 |
| EAQ05838.1 | EAQ07757.1 | SKA53_07027 | SKA53_13008 | COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases. | Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases. | 0.886 |
| EAQ05838.1 | EAQ08072.1 | SKA53_07027 | SKA53_10119 | COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases. | Methyltransferase, UbiE/COQ5 family; COG0500 SAM-dependent methyltransferases. | 0.851 |
| EAQ05838.1 | EAQ08163.1 | SKA53_07027 | SKA53_10574 | COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases. | 2-polyprenylphenol 6-hydroxylase; COG0661 Predicted unusual protein kinase. | 0.466 |
| EAQ05838.1 | ubiA | SKA53_07027 | SKA53_14256 | COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases. | 4-hydroxybenzoate polyprenyl transferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.448 |
| EAQ05838.1 | ubiE | SKA53_07027 | SKA53_10569 | COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases. | Ubiquinone/menaquinone biosynthesis methyltransferase UbiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). | 0.940 |
| EAQ05838.1 | ubiG | SKA53_07027 | SKA53_11713 | COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases. | 3-demethylubiquinone-9 3-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. | 0.954 |
| EAQ06398.1 | EAQ05838.1 | SKA53_04903 | SKA53_07027 | Aromatic-rich family protein; COG2867 Oligoketide cyclase/lipid transport protein. | COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases. | 0.408 |
| EAQ06398.1 | EAQ07757.1 | SKA53_04903 | SKA53_13008 | Aromatic-rich family protein; COG2867 Oligoketide cyclase/lipid transport protein. | Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases. | 0.434 |
| EAQ06398.1 | EAQ08163.1 | SKA53_04903 | SKA53_10574 | Aromatic-rich family protein; COG2867 Oligoketide cyclase/lipid transport protein. | 2-polyprenylphenol 6-hydroxylase; COG0661 Predicted unusual protein kinase. | 0.464 |
| EAQ06398.1 | ubiA | SKA53_04903 | SKA53_14256 | Aromatic-rich family protein; COG2867 Oligoketide cyclase/lipid transport protein. | 4-hydroxybenzoate polyprenyl transferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.587 |
| EAQ06398.1 | ubiG | SKA53_04903 | SKA53_11713 | Aromatic-rich family protein; COG2867 Oligoketide cyclase/lipid transport protein. | 3-demethylubiquinone-9 3-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. | 0.659 |
| EAQ07497.1 | ubiG | SKA53_11708 | SKA53_11713 | Proline iminopeptidase; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); Belongs to the peptidase S33 family. | 3-demethylubiquinone-9 3-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. | 0.652 |
| EAQ07576.1 | ubiA | SKA53_12103 | SKA53_14256 | Magnesium-chelatase, subunit D; COG1239 Mg-chelatase subunit ChlI. | 4-hydroxybenzoate polyprenyl transferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.698 |
| EAQ07576.1 | ubiG | SKA53_12103 | SKA53_11713 | Magnesium-chelatase, subunit D; COG1239 Mg-chelatase subunit ChlI. | 3-demethylubiquinone-9 3-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. | 0.875 |
| EAQ07757.1 | EAQ05838.1 | SKA53_13008 | SKA53_07027 | Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases. | COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases. | 0.886 |
| EAQ07757.1 | EAQ06398.1 | SKA53_13008 | SKA53_04903 | Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases. | Aromatic-rich family protein; COG2867 Oligoketide cyclase/lipid transport protein. | 0.434 |
| EAQ07757.1 | EAQ08072.1 | SKA53_13008 | SKA53_10119 | Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases. | Methyltransferase, UbiE/COQ5 family; COG0500 SAM-dependent methyltransferases. | 0.851 |
| EAQ07757.1 | ubiA | SKA53_13008 | SKA53_14256 | Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases. | 4-hydroxybenzoate polyprenyl transferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.655 |
| EAQ07757.1 | ubiE | SKA53_13008 | SKA53_10569 | Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases. | Ubiquinone/menaquinone biosynthesis methyltransferase UbiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). | 0.963 |