| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAQ07142.1 | EAQ07513.1 | SKA53_02061 | SKA53_11788 | S4 domain protein; COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog). | Chaperonin, 33 kDa; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress; Belongs to the HSP33 family. | 0.890 |
| EAQ07142.1 | grpE | SKA53_02061 | SKA53_11833 | S4 domain protein; COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog). | Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...] | 0.666 |
| EAQ07142.1 | hslU | SKA53_02061 | SKA53_11943 | S4 domain protein; COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog). | ATP-dependent protease ATP-binding subunit; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. | 0.720 |
| EAQ07142.1 | hslV | SKA53_02061 | SKA53_11953 | S4 domain protein; COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog). | ATP-dependent protease peptidase subunit; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. | 0.813 |
| EAQ07508.1 | EAQ07509.1 | SKA53_11763 | SKA53_11768 | 23S rRNA (Uracil-5-)-methyltransferase rumA; COG2265 SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. | ABC multidrug efflux pump, fused ATPase and inner membrane subunits; COG1132 ABC-type multidrug transport system, ATPase and permease components. | 0.814 |
| EAQ07508.1 | EAQ07510.1 | SKA53_11763 | SKA53_11773 | 23S rRNA (Uracil-5-)-methyltransferase rumA; COG2265 SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. | ABC transporter, transmembrane ATP-binding protein; COG1132 ABC-type multidrug transport system, ATPase and permease components. | 0.814 |
| EAQ07508.1 | EAQ07511.1 | SKA53_11763 | SKA53_11778 | 23S rRNA (Uracil-5-)-methyltransferase rumA; COG2265 SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. | polyA polymerase family protein; COG0617 tRNA nucleotidyltransferase/poly(A) polymerase; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. | 0.767 |
| EAQ07508.1 | EAQ07512.1 | SKA53_11763 | SKA53_11783 | 23S rRNA (Uracil-5-)-methyltransferase rumA; COG2265 SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. | Hydrolase, NUDIX family; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes. | 0.743 |
| EAQ07508.1 | EAQ07513.1 | SKA53_11763 | SKA53_11788 | 23S rRNA (Uracil-5-)-methyltransferase rumA; COG2265 SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. | Chaperonin, 33 kDa; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress; Belongs to the HSP33 family. | 0.804 |
| EAQ07508.1 | EAQ07514.1 | SKA53_11763 | SKA53_11793 | 23S rRNA (Uracil-5-)-methyltransferase rumA; COG2265 SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. | Hydrolase, NUDIX family; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; Belongs to the Nudix hydrolase family. | 0.578 |
| EAQ07509.1 | EAQ07508.1 | SKA53_11768 | SKA53_11763 | ABC multidrug efflux pump, fused ATPase and inner membrane subunits; COG1132 ABC-type multidrug transport system, ATPase and permease components. | 23S rRNA (Uracil-5-)-methyltransferase rumA; COG2265 SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. | 0.814 |
| EAQ07509.1 | EAQ07510.1 | SKA53_11768 | SKA53_11773 | ABC multidrug efflux pump, fused ATPase and inner membrane subunits; COG1132 ABC-type multidrug transport system, ATPase and permease components. | ABC transporter, transmembrane ATP-binding protein; COG1132 ABC-type multidrug transport system, ATPase and permease components. | 0.793 |
| EAQ07509.1 | EAQ07511.1 | SKA53_11768 | SKA53_11778 | ABC multidrug efflux pump, fused ATPase and inner membrane subunits; COG1132 ABC-type multidrug transport system, ATPase and permease components. | polyA polymerase family protein; COG0617 tRNA nucleotidyltransferase/poly(A) polymerase; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. | 0.671 |
| EAQ07509.1 | EAQ07512.1 | SKA53_11768 | SKA53_11783 | ABC multidrug efflux pump, fused ATPase and inner membrane subunits; COG1132 ABC-type multidrug transport system, ATPase and permease components. | Hydrolase, NUDIX family; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes. | 0.701 |
| EAQ07509.1 | EAQ07513.1 | SKA53_11768 | SKA53_11788 | ABC multidrug efflux pump, fused ATPase and inner membrane subunits; COG1132 ABC-type multidrug transport system, ATPase and permease components. | Chaperonin, 33 kDa; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress; Belongs to the HSP33 family. | 0.669 |
| EAQ07509.1 | EAQ07514.1 | SKA53_11768 | SKA53_11793 | ABC multidrug efflux pump, fused ATPase and inner membrane subunits; COG1132 ABC-type multidrug transport system, ATPase and permease components. | Hydrolase, NUDIX family; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; Belongs to the Nudix hydrolase family. | 0.509 |
| EAQ07510.1 | EAQ07508.1 | SKA53_11773 | SKA53_11763 | ABC transporter, transmembrane ATP-binding protein; COG1132 ABC-type multidrug transport system, ATPase and permease components. | 23S rRNA (Uracil-5-)-methyltransferase rumA; COG2265 SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. | 0.814 |
| EAQ07510.1 | EAQ07509.1 | SKA53_11773 | SKA53_11768 | ABC transporter, transmembrane ATP-binding protein; COG1132 ABC-type multidrug transport system, ATPase and permease components. | ABC multidrug efflux pump, fused ATPase and inner membrane subunits; COG1132 ABC-type multidrug transport system, ATPase and permease components. | 0.793 |
| EAQ07510.1 | EAQ07511.1 | SKA53_11773 | SKA53_11778 | ABC transporter, transmembrane ATP-binding protein; COG1132 ABC-type multidrug transport system, ATPase and permease components. | polyA polymerase family protein; COG0617 tRNA nucleotidyltransferase/poly(A) polymerase; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. | 0.671 |
| EAQ07510.1 | EAQ07512.1 | SKA53_11773 | SKA53_11783 | ABC transporter, transmembrane ATP-binding protein; COG1132 ABC-type multidrug transport system, ATPase and permease components. | Hydrolase, NUDIX family; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes. | 0.701 |