| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAQ05542.1 | EAQ07280.1 | SKA53_00609 | SKA53_02751 | COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 5-aminolevulinate synthase; COG0156 7-keto-8-aminopelargonate synthetase and related enzymes. | 0.845 |
| EAQ05542.1 | EAQ07573.1 | SKA53_00609 | SKA53_12088 | COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 5-aminolevulinate synthase; COG0156 7-keto-8-aminopelargonate synthetase and related enzymes. | 0.845 |
| EAQ06061.1 | EAQ07280.1 | SKA53_08146 | SKA53_02751 | Hypothetical protein; COG0642 Signal transduction histidine kinase. | 5-aminolevulinate synthase; COG0156 7-keto-8-aminopelargonate synthetase and related enzymes. | 0.922 |
| EAQ06061.1 | EAQ07573.1 | SKA53_08146 | SKA53_12088 | Hypothetical protein; COG0642 Signal transduction histidine kinase. | 5-aminolevulinate synthase; COG0156 7-keto-8-aminopelargonate synthetase and related enzymes. | 0.931 |
| EAQ06061.1 | EAQ08009.1 | SKA53_08146 | SKA53_09804 | Hypothetical protein; COG0642 Signal transduction histidine kinase. | COG0642 Signal transduction histidine kinase. | 0.999 |
| EAQ06347.1 | EAQ07280.1 | SKA53_04648 | SKA53_02751 | COG0113 Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | 5-aminolevulinate synthase; COG0156 7-keto-8-aminopelargonate synthetase and related enzymes. | 0.895 |
| EAQ06347.1 | EAQ07573.1 | SKA53_04648 | SKA53_12088 | COG0113 Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | 5-aminolevulinate synthase; COG0156 7-keto-8-aminopelargonate synthetase and related enzymes. | 0.895 |
| EAQ07280.1 | EAQ05542.1 | SKA53_02751 | SKA53_00609 | 5-aminolevulinate synthase; COG0156 7-keto-8-aminopelargonate synthetase and related enzymes. | COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.845 |
| EAQ07280.1 | EAQ06061.1 | SKA53_02751 | SKA53_08146 | 5-aminolevulinate synthase; COG0156 7-keto-8-aminopelargonate synthetase and related enzymes. | Hypothetical protein; COG0642 Signal transduction histidine kinase. | 0.922 |
| EAQ07280.1 | EAQ06347.1 | SKA53_02751 | SKA53_04648 | 5-aminolevulinate synthase; COG0156 7-keto-8-aminopelargonate synthetase and related enzymes. | COG0113 Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | 0.895 |
| EAQ07280.1 | EAQ07573.1 | SKA53_02751 | SKA53_12088 | 5-aminolevulinate synthase; COG0156 7-keto-8-aminopelargonate synthetase and related enzymes. | 5-aminolevulinate synthase; COG0156 7-keto-8-aminopelargonate synthetase and related enzymes. | 0.754 |
| EAQ07280.1 | EAQ07731.1 | SKA53_02751 | SKA53_12878 | 5-aminolevulinate synthase; COG0156 7-keto-8-aminopelargonate synthetase and related enzymes. | L-threonine aldolase, low-specificity, putative; COG2008 Threonine aldolase. | 0.780 |
| EAQ07280.1 | EAQ07887.1 | SKA53_02751 | SKA53_09194 | 5-aminolevulinate synthase; COG0156 7-keto-8-aminopelargonate synthetase and related enzymes. | Hypothetical protein; COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.845 |
| EAQ07280.1 | EAQ08009.1 | SKA53_02751 | SKA53_09804 | 5-aminolevulinate synthase; COG0156 7-keto-8-aminopelargonate synthetase and related enzymes. | COG0642 Signal transduction histidine kinase. | 0.733 |
| EAQ07280.1 | cobD | SKA53_02751 | SKA53_10054 | 5-aminolevulinate synthase; COG0156 7-keto-8-aminopelargonate synthetase and related enzymes. | Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.755 |
| EAQ07280.1 | glyA | SKA53_02751 | SKA53_09419 | 5-aminolevulinate synthase; COG0156 7-keto-8-aminopelargonate synthetase and related enzymes. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.702 |
| EAQ07572.1 | EAQ07573.1 | SKA53_12083 | SKA53_12088 | Hypothetical protein; COG0477 Permeases of the major facilitator superfamily. | 5-aminolevulinate synthase; COG0156 7-keto-8-aminopelargonate synthetase and related enzymes. | 0.795 |
| EAQ07573.1 | EAQ05542.1 | SKA53_12088 | SKA53_00609 | 5-aminolevulinate synthase; COG0156 7-keto-8-aminopelargonate synthetase and related enzymes. | COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.845 |
| EAQ07573.1 | EAQ06061.1 | SKA53_12088 | SKA53_08146 | 5-aminolevulinate synthase; COG0156 7-keto-8-aminopelargonate synthetase and related enzymes. | Hypothetical protein; COG0642 Signal transduction histidine kinase. | 0.931 |
| EAQ07573.1 | EAQ06347.1 | SKA53_12088 | SKA53_04648 | 5-aminolevulinate synthase; COG0156 7-keto-8-aminopelargonate synthetase and related enzymes. | COG0113 Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | 0.895 |