STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
amnAMP nucleosidase; Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations. (493 aa)    
Predicted Functional Partners:
ade
COG1001 Adenine deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.
    
 0.978
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
   
 0.909
EAQ06533.1
COG1957 Inosine-uridine nucleoside N-ribohydrolase.
  
  
 0.887
deoD
COG0813 Purine-nucleoside phosphorylase.
   
 
  0.853
EAQ07921.1
COG1816 Adenosine deaminase.
   
 
 0.813
mtnP
5'-methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
    
 0.779
EAQ06798.1
Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
    
 0.779
EAQ07581.1
COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog).
       0.688
EAQ07584.1
DNA-binding protein HU; COG0776 Bacterial nucleoid DNA-binding protein; Belongs to the bacterial histone-like protein family.
       0.673
EAQ07580.1
Squalene/phytoene synthase; COG1562 Phytoene/squalene synthetase.
     
 0.616
Your Current Organism:
Yoonia vestfoldensis SKA53
NCBI taxonomy Id: 314232
Other names: Loktanella vestfoldensis SKA53, Y. vestfoldensis SKA53
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