| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAQ05746.1 | EAQ07676.1 | SKA53_06567 | SKA53_12603 | Putative HolB DNA polymerase III delta prime subunit; COG0470 ATPase involved in DNA replication. | COG0514 Superfamily II DNA helicase. | 0.875 |
| EAQ05746.1 | EAQ08157.1 | SKA53_06567 | SKA53_10544 | Putative HolB DNA polymerase III delta prime subunit; COG0470 ATPase involved in DNA replication. | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.990 |
| EAQ05746.1 | mutL | SKA53_06567 | SKA53_12663 | Putative HolB DNA polymerase III delta prime subunit; COG0470 ATPase involved in DNA replication. | DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.619 |
| EAQ05746.1 | polA | SKA53_06567 | SKA53_15116 | Putative HolB DNA polymerase III delta prime subunit; COG0470 ATPase involved in DNA replication. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.926 |
| EAQ05746.1 | recA | SKA53_06567 | SKA53_03339 | Putative HolB DNA polymerase III delta prime subunit; COG0470 ATPase involved in DNA replication. | Recombinase A; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.588 |
| EAQ05746.1 | topA | SKA53_06567 | SKA53_08441 | Putative HolB DNA polymerase III delta prime subunit; COG0470 ATPase involved in DNA replication. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.701 |
| EAQ05900.1 | EAQ06794.1 | SKA53_07341 | SKA53_14641 | Putative uvrD/DNA Helicase II; COG0210 Superfamily I DNA and RNA helicases. | ATPase; COG0507 ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member. | 0.837 |
| EAQ05900.1 | EAQ07676.1 | SKA53_07341 | SKA53_12603 | Putative uvrD/DNA Helicase II; COG0210 Superfamily I DNA and RNA helicases. | COG0514 Superfamily II DNA helicase. | 0.946 |
| EAQ05900.1 | EAQ08157.1 | SKA53_07341 | SKA53_10544 | Putative uvrD/DNA Helicase II; COG0210 Superfamily I DNA and RNA helicases. | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.907 |
| EAQ05900.1 | mutL | SKA53_07341 | SKA53_12663 | Putative uvrD/DNA Helicase II; COG0210 Superfamily I DNA and RNA helicases. | DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.901 |
| EAQ05900.1 | polA | SKA53_07341 | SKA53_15116 | Putative uvrD/DNA Helicase II; COG0210 Superfamily I DNA and RNA helicases. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.886 |
| EAQ05900.1 | recA | SKA53_07341 | SKA53_03339 | Putative uvrD/DNA Helicase II; COG0210 Superfamily I DNA and RNA helicases. | Recombinase A; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.906 |
| EAQ05900.1 | topA | SKA53_07341 | SKA53_08441 | Putative uvrD/DNA Helicase II; COG0210 Superfamily I DNA and RNA helicases. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.932 |
| EAQ06457.1 | EAQ07676.1 | SKA53_05198 | SKA53_12603 | DEAD-box protein, ATP-independent RNA helicase; COG0513 Superfamily II DNA and RNA helicases; Belongs to the DEAD box helicase family. | COG0514 Superfamily II DNA helicase. | 0.919 |
| EAQ06457.1 | topA | SKA53_05198 | SKA53_08441 | DEAD-box protein, ATP-independent RNA helicase; COG0513 Superfamily II DNA and RNA helicases; Belongs to the DEAD box helicase family. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.538 |
| EAQ06794.1 | EAQ05900.1 | SKA53_14641 | SKA53_07341 | ATPase; COG0507 ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member. | Putative uvrD/DNA Helicase II; COG0210 Superfamily I DNA and RNA helicases. | 0.837 |
| EAQ06794.1 | EAQ07676.1 | SKA53_14641 | SKA53_12603 | ATPase; COG0507 ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member. | COG0514 Superfamily II DNA helicase. | 0.882 |
| EAQ06794.1 | EAQ08157.1 | SKA53_14641 | SKA53_10544 | ATPase; COG0507 ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member. | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.903 |
| EAQ06794.1 | mutL | SKA53_14641 | SKA53_12663 | ATPase; COG0507 ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member. | DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.419 |
| EAQ06794.1 | polA | SKA53_14641 | SKA53_15116 | ATPase; COG0507 ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.658 |