Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EAQ07731.1L-threonine aldolase, low-specificity, putative; COG2008 Threonine aldolase. (348 aa)    
Predicted Functional Partners:
EAQ06110.1
COG0498 Threonine synthase.
  
 
 0.892
EAQ07733.1
Riboflavin biosynthesis protein RibF; COG0196 FAD synthase; Belongs to the ribF family.
     
 0.878
EAQ05534.1
COG1171 Threonine dehydratase.
   
 
 0.875
EAQ08025.1
Serine--glyoxylate transaminase, putative; COG0075 Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase.
    
 0.862
EAQ07732.1
Hypothetical protein; Belongs to the UPF0260 family.
       0.853
EAQ05300.1
COG4583 Sarcosine oxidase gamma subunit.
  
  
  0.836
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
    
 0.818
glyA-2
Hypothetical protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
    
 0.818
EAQ08234.1
COG4583 Sarcosine oxidase gamma subunit.
     
  0.815
EAQ07113.1
COG4311 Sarcosine oxidase delta subunit.
    
  0.808
Your Current Organism:
Yoonia vestfoldensis SKA53
NCBI taxonomy Id: 314232
Other names: Loktanella vestfoldensis SKA53, Y. vestfoldensis SKA53
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