| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAQ06711.1 | EAQ06712.1 | SKA53_14226 | SKA53_14231 | Metallo-beta-lactamase family protein; COG0491 Zn-dependent hydrolases, including glyoxylases. | COG1960 Acyl-CoA dehydrogenases. | 0.832 |
| EAQ06711.1 | EAQ06713.1 | SKA53_14226 | SKA53_14236 | Metallo-beta-lactamase family protein; COG0491 Zn-dependent hydrolases, including glyoxylases. | Sua5/YciO/YrdC family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | 0.705 |
| EAQ06712.1 | EAQ06711.1 | SKA53_14231 | SKA53_14226 | COG1960 Acyl-CoA dehydrogenases. | Metallo-beta-lactamase family protein; COG0491 Zn-dependent hydrolases, including glyoxylases. | 0.832 |
| EAQ06712.1 | EAQ06713.1 | SKA53_14231 | SKA53_14236 | COG1960 Acyl-CoA dehydrogenases. | Sua5/YciO/YrdC family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | 0.539 |
| EAQ06713.1 | EAQ06711.1 | SKA53_14236 | SKA53_14226 | Sua5/YciO/YrdC family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | Metallo-beta-lactamase family protein; COG0491 Zn-dependent hydrolases, including glyoxylases. | 0.705 |
| EAQ06713.1 | EAQ06712.1 | SKA53_14236 | SKA53_14231 | Sua5/YciO/YrdC family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | COG1960 Acyl-CoA dehydrogenases. | 0.539 |
| EAQ06713.1 | EAQ06805.1 | SKA53_14236 | SKA53_14696 | Sua5/YciO/YrdC family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | Protease, putative; COG1214 Inactive homolog of metal-dependent proteases, putative molecular chaperone. | 0.546 |
| EAQ06713.1 | EAQ07715.1 | SKA53_14236 | SKA53_12798 | Sua5/YciO/YrdC family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | Mannose-6-phosphate isomerase /; COG0836 Mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family. | 0.470 |
| EAQ06713.1 | glmS | SKA53_14236 | SKA53_06232 | Sua5/YciO/YrdC family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | D-fructose-6-phosphate amidotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.495 |
| EAQ06713.1 | glyA | SKA53_14236 | SKA53_09419 | Sua5/YciO/YrdC family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.474 |
| EAQ06713.1 | glyA-2 | SKA53_14236 | SKA53_10924 | Sua5/YciO/YrdC family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | Hypothetical protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.483 |
| EAQ06713.1 | polA | SKA53_14236 | SKA53_15116 | Sua5/YciO/YrdC family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.528 |
| EAQ06713.1 | prmC | SKA53_14236 | SKA53_05283 | Sua5/YciO/YrdC family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | Modification methylase, HemK family; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily. | 0.773 |
| EAQ06713.1 | tsaD | SKA53_14236 | SKA53_11503 | Sua5/YciO/YrdC family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | O-sialoglycoprotein endopeptidase, putative; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.508 |
| EAQ06805.1 | EAQ06713.1 | SKA53_14696 | SKA53_14236 | Protease, putative; COG1214 Inactive homolog of metal-dependent proteases, putative molecular chaperone. | Sua5/YciO/YrdC family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | 0.546 |
| EAQ06805.1 | tsaD | SKA53_14696 | SKA53_11503 | Protease, putative; COG1214 Inactive homolog of metal-dependent proteases, putative molecular chaperone. | O-sialoglycoprotein endopeptidase, putative; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.991 |
| EAQ07715.1 | EAQ06713.1 | SKA53_12798 | SKA53_14236 | Mannose-6-phosphate isomerase /; COG0836 Mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family. | Sua5/YciO/YrdC family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | 0.470 |
| EAQ07715.1 | glmS | SKA53_12798 | SKA53_06232 | Mannose-6-phosphate isomerase /; COG0836 Mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family. | D-fructose-6-phosphate amidotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.902 |
| glmS | EAQ06713.1 | SKA53_06232 | SKA53_14236 | D-fructose-6-phosphate amidotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | Sua5/YciO/YrdC family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | 0.495 |
| glmS | EAQ07715.1 | SKA53_06232 | SKA53_12798 | D-fructose-6-phosphate amidotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | Mannose-6-phosphate isomerase /; COG0836 Mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family. | 0.902 |