| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAQ05729.1 | EAQ06714.1 | SKA53_06482 | SKA53_14241 | Hypothetical protein; COG0702 Predicted nucleoside-diphosphate-sugar epimerases. | COG2249 putative NADPH-quinone reductase (modulator of drug activity B). | 0.820 |
| EAQ05729.1 | nuoB | SKA53_06482 | SKA53_06182 | Hypothetical protein; COG0702 Predicted nucleoside-diphosphate-sugar epimerases. | NADH dehydrogenase beta subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. | 0.919 |
| EAQ05729.1 | ubiE | SKA53_06482 | SKA53_10569 | Hypothetical protein; COG0702 Predicted nucleoside-diphosphate-sugar epimerases. | Ubiquinone/menaquinone biosynthesis methyltransferase UbiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). | 0.815 |
| EAQ06676.1 | EAQ06714.1 | SKA53_14051 | SKA53_14241 | Electrotransfer ubiquinone oxidoreductase family protein; Accepts electrons from ETF and reduces ubiquinone. | COG2249 putative NADPH-quinone reductase (modulator of drug activity B). | 0.426 |
| EAQ06676.1 | ubiA | SKA53_14051 | SKA53_14256 | Electrotransfer ubiquinone oxidoreductase family protein; Accepts electrons from ETF and reduces ubiquinone. | 4-hydroxybenzoate polyprenyl transferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.710 |
| EAQ06714.1 | EAQ05729.1 | SKA53_14241 | SKA53_06482 | COG2249 putative NADPH-quinone reductase (modulator of drug activity B). | Hypothetical protein; COG0702 Predicted nucleoside-diphosphate-sugar epimerases. | 0.820 |
| EAQ06714.1 | EAQ06676.1 | SKA53_14241 | SKA53_14051 | COG2249 putative NADPH-quinone reductase (modulator of drug activity B). | Electrotransfer ubiquinone oxidoreductase family protein; Accepts electrons from ETF and reduces ubiquinone. | 0.426 |
| EAQ06714.1 | EAQ06715.1 | SKA53_14241 | SKA53_14246 | COG2249 putative NADPH-quinone reductase (modulator of drug activity B). | Hypothetical protein; COG0840 Methyl-accepting chemotaxis protein. | 0.773 |
| EAQ06714.1 | EAQ06716.1 | SKA53_14241 | SKA53_14251 | COG2249 putative NADPH-quinone reductase (modulator of drug activity B). | OmpA domain protein; COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)proteins. | 0.773 |
| EAQ06714.1 | EAQ06718.1 | SKA53_14241 | SKA53_14261 | COG2249 putative NADPH-quinone reductase (modulator of drug activity B). | Hypothetical protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | 0.455 |
| EAQ06714.1 | EAQ06719.1 | SKA53_14241 | SKA53_14266 | COG2249 putative NADPH-quinone reductase (modulator of drug activity B). | Acetyltransferase, GNAT family; COG0454 Histone acetyltransferase HPA2 and related acetyltransferases. | 0.455 |
| EAQ06714.1 | EAQ06720.1 | SKA53_14241 | SKA53_14271 | COG2249 putative NADPH-quinone reductase (modulator of drug activity B). | Hypothetical protein. | 0.455 |
| EAQ06714.1 | nuoB | SKA53_14241 | SKA53_06182 | COG2249 putative NADPH-quinone reductase (modulator of drug activity B). | NADH dehydrogenase beta subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. | 0.470 |
| EAQ06714.1 | ubiA | SKA53_14241 | SKA53_14256 | COG2249 putative NADPH-quinone reductase (modulator of drug activity B). | 4-hydroxybenzoate polyprenyl transferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.603 |
| EAQ06714.1 | ubiE | SKA53_14241 | SKA53_10569 | COG2249 putative NADPH-quinone reductase (modulator of drug activity B). | Ubiquinone/menaquinone biosynthesis methyltransferase UbiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). | 0.815 |
| EAQ06715.1 | EAQ06714.1 | SKA53_14246 | SKA53_14241 | Hypothetical protein; COG0840 Methyl-accepting chemotaxis protein. | COG2249 putative NADPH-quinone reductase (modulator of drug activity B). | 0.773 |
| EAQ06715.1 | EAQ06716.1 | SKA53_14246 | SKA53_14251 | Hypothetical protein; COG0840 Methyl-accepting chemotaxis protein. | OmpA domain protein; COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)proteins. | 0.902 |
| EAQ06715.1 | EAQ06718.1 | SKA53_14246 | SKA53_14261 | Hypothetical protein; COG0840 Methyl-accepting chemotaxis protein. | Hypothetical protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | 0.647 |
| EAQ06715.1 | EAQ06719.1 | SKA53_14246 | SKA53_14266 | Hypothetical protein; COG0840 Methyl-accepting chemotaxis protein. | Acetyltransferase, GNAT family; COG0454 Histone acetyltransferase HPA2 and related acetyltransferases. | 0.539 |
| EAQ06715.1 | EAQ06720.1 | SKA53_14246 | SKA53_14271 | Hypothetical protein; COG0840 Methyl-accepting chemotaxis protein. | Hypothetical protein. | 0.715 |