| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAQ06556.1 | rplC | SKA53_13451 | SKA53_13328 | COG0099 Ribosomal protein S13; Belongs to the universal ribosomal protein uS13 family. | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 0.998 |
| EAQ06556.1 | rplF | SKA53_13451 | SKA53_13416 | COG0099 Ribosomal protein S13; Belongs to the universal ribosomal protein uS13 family. | 50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. | 0.999 |
| EAQ06556.1 | rplM | SKA53_13451 | SKA53_04443 | COG0099 Ribosomal protein S13; Belongs to the universal ribosomal protein uS13 family. | 50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.999 |
| EAQ06556.1 | rplS | SKA53_13451 | SKA53_14971 | COG0099 Ribosomal protein S13; Belongs to the universal ribosomal protein uS13 family. | 50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. | 0.997 |
| EAQ06556.1 | rplT | SKA53_13451 | SKA53_10219 | COG0099 Ribosomal protein S13; Belongs to the universal ribosomal protein uS13 family. | 50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. | 0.998 |
| EAQ06556.1 | rplU | SKA53_13451 | SKA53_04353 | COG0099 Ribosomal protein S13; Belongs to the universal ribosomal protein uS13 family. | Ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.998 |
| EAQ06556.1 | rpsB | SKA53_13451 | SKA53_04723 | COG0099 Ribosomal protein S13; Belongs to the universal ribosomal protein uS13 family. | COG0052 Ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family. | 0.999 |
| EAQ06556.1 | rpsO | SKA53_13451 | SKA53_12563 | COG0099 Ribosomal protein S13; Belongs to the universal ribosomal protein uS13 family. | Ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome. | 0.999 |
| EAQ06556.1 | rpsQ | SKA53_13451 | SKA53_13386 | COG0099 Ribosomal protein S13; Belongs to the universal ribosomal protein uS13 family. | Ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. | 0.999 |
| EAQ06556.1 | smpB | SKA53_13451 | SKA53_14401 | COG0099 Ribosomal protein S13; Belongs to the universal ribosomal protein uS13 family. | SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...] | 0.980 |
| rplC | EAQ06556.1 | SKA53_13328 | SKA53_13451 | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | COG0099 Ribosomal protein S13; Belongs to the universal ribosomal protein uS13 family. | 0.998 |
| rplC | rplF | SKA53_13328 | SKA53_13416 | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. | 0.999 |
| rplC | rplM | SKA53_13328 | SKA53_04443 | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.999 |
| rplC | rplS | SKA53_13328 | SKA53_14971 | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. | 0.997 |
| rplC | rplT | SKA53_13328 | SKA53_10219 | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. | 0.998 |
| rplC | rplU | SKA53_13328 | SKA53_04353 | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | Ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.998 |
| rplC | rpsB | SKA53_13328 | SKA53_04723 | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | COG0052 Ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family. | 0.998 |
| rplC | rpsO | SKA53_13328 | SKA53_12563 | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | Ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome. | 0.998 |
| rplC | rpsQ | SKA53_13328 | SKA53_13386 | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | Ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. | 0.999 |
| rplC | smpB | SKA53_13328 | SKA53_14401 | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...] | 0.978 |
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