Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EAQ06777.1COG2301 Citrate lyase beta subunit; Belongs to the HpcH/HpaI aldolase family. (280 aa)    
Predicted Functional Partners:
EAQ06780.1
MaoC family protein; COG2030 Acyl dehydratase.
 
 
 0.977
EAQ07926.1
Phosphate acetyltransferase; COG0281 Malic enzyme.
  
 
 0.840
EAQ07520.1
Phosphate acetyltransferase; COG0281 Malic enzyme.
  
 
 0.840
EAQ06778.1
NnrU family protein; COG4094 Predicted membrane protein.
       0.814
EAQ06779.1
Hypothetical protein; COG5515 Uncharacterized conserved small protein.
       0.814
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
  
 
 0.799
EAQ06743.1
COG2301 Citrate lyase beta subunit; Belongs to the HpcH/HpaI aldolase family.
  
  
 
0.779
sucC
succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
    
 0.777
fumC
Fumarate lyase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
  
 
 0.769
sucD
Succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
 
 0.764
Your Current Organism:
Yoonia vestfoldensis SKA53
NCBI taxonomy Id: 314232
Other names: Loktanella vestfoldensis SKA53, Y. vestfoldensis SKA53
Server load: low (14%) [HD]