| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAQ05751.1 | EAQ06243.1 | SKA53_06592 | SKA53_04128 | Hypothetical protein; COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit. | 3-ketosteroid dehydrogenase, putative; COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit. | 0.643 |
| EAQ05751.1 | EAQ06744.1 | SKA53_06592 | SKA53_14391 | Hypothetical protein; COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit. | COG1448 Aspartate/tyrosine/aromatic aminotransferase. | 0.425 |
| EAQ05751.1 | EAQ06770.1 | SKA53_06592 | SKA53_14521 | Hypothetical protein; COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit. | COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes. | 0.866 |
| EAQ05751.1 | EAQ06781.1 | SKA53_06592 | SKA53_14576 | Hypothetical protein; COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit. | COG2009 Succinate dehydrogenase/fumarate reductase, cytochrome b subunit. | 0.996 |
| EAQ05751.1 | EAQ06782.1 | SKA53_06592 | SKA53_14581 | Hypothetical protein; COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit. | COG2142 Succinate dehydrogenase, hydrophobic anchor subunit. | 0.905 |
| EAQ05751.1 | EAQ06786.1 | SKA53_06592 | SKA53_14601 | Hypothetical protein; COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit. | COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | 0.996 |
| EAQ05751.1 | fumC | SKA53_06592 | SKA53_03499 | Hypothetical protein; COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit. | Fumarate lyase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 0.775 |
| EAQ05751.1 | sucC | SKA53_06592 | SKA53_14531 | Hypothetical protein; COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit. | succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.800 |
| EAQ05751.1 | sucD | SKA53_06592 | SKA53_14526 | Hypothetical protein; COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit. | Succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.791 |
| EAQ06243.1 | EAQ05751.1 | SKA53_04128 | SKA53_06592 | 3-ketosteroid dehydrogenase, putative; COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit. | Hypothetical protein; COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit. | 0.643 |
| EAQ06243.1 | EAQ06744.1 | SKA53_04128 | SKA53_14391 | 3-ketosteroid dehydrogenase, putative; COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit. | COG1448 Aspartate/tyrosine/aromatic aminotransferase. | 0.877 |
| EAQ06243.1 | EAQ06770.1 | SKA53_04128 | SKA53_14521 | 3-ketosteroid dehydrogenase, putative; COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit. | COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes. | 0.866 |
| EAQ06243.1 | EAQ06781.1 | SKA53_04128 | SKA53_14576 | 3-ketosteroid dehydrogenase, putative; COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit. | COG2009 Succinate dehydrogenase/fumarate reductase, cytochrome b subunit. | 0.998 |
| EAQ06243.1 | EAQ06782.1 | SKA53_04128 | SKA53_14581 | 3-ketosteroid dehydrogenase, putative; COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit. | COG2142 Succinate dehydrogenase, hydrophobic anchor subunit. | 0.980 |
| EAQ06243.1 | EAQ06786.1 | SKA53_04128 | SKA53_14601 | 3-ketosteroid dehydrogenase, putative; COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit. | COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | 0.998 |
| EAQ06243.1 | fumC | SKA53_04128 | SKA53_03499 | 3-ketosteroid dehydrogenase, putative; COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit. | Fumarate lyase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 0.952 |
| EAQ06243.1 | sucC | SKA53_04128 | SKA53_14531 | 3-ketosteroid dehydrogenase, putative; COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit. | succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.958 |
| EAQ06243.1 | sucD | SKA53_04128 | SKA53_14526 | 3-ketosteroid dehydrogenase, putative; COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit. | Succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.956 |
| EAQ06744.1 | EAQ05751.1 | SKA53_14391 | SKA53_06592 | COG1448 Aspartate/tyrosine/aromatic aminotransferase. | Hypothetical protein; COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit. | 0.425 |
| EAQ06744.1 | EAQ06243.1 | SKA53_14391 | SKA53_04128 | COG1448 Aspartate/tyrosine/aromatic aminotransferase. | 3-ketosteroid dehydrogenase, putative; COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit. | 0.877 |