| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAQ05758.1 | EAQ05902.1 | SKA53_06627 | SKA53_07351 | Hypothetical protein; COG1082 Sugar phosphate isomerases/epimerases. | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | 0.581 |
| EAQ05758.1 | EAQ06790.1 | SKA53_06627 | SKA53_14621 | Hypothetical protein; COG1082 Sugar phosphate isomerases/epimerases. | COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit. | 0.918 |
| EAQ05758.1 | EAQ07066.1 | SKA53_06627 | SKA53_01681 | Hypothetical protein; COG1082 Sugar phosphate isomerases/epimerases. | COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit. | 0.918 |
| EAQ05758.1 | EAQ07315.1 | SKA53_06627 | SKA53_02926 | Hypothetical protein; COG1082 Sugar phosphate isomerases/epimerases. | COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits. | 0.898 |
| EAQ05758.1 | EAQ07964.1 | SKA53_06627 | SKA53_09579 | Hypothetical protein; COG1082 Sugar phosphate isomerases/epimerases. | methylmalonyl-CoA epimerase; COG0346 Lactoylglutathione lyase and related lyases. | 0.453 |
| EAQ05758.1 | sucC | SKA53_06627 | SKA53_14531 | Hypothetical protein; COG1082 Sugar phosphate isomerases/epimerases. | succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.613 |
| EAQ05758.1 | sucD | SKA53_06627 | SKA53_14526 | Hypothetical protein; COG1082 Sugar phosphate isomerases/epimerases. | Succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.590 |
| EAQ05902.1 | EAQ05758.1 | SKA53_07351 | SKA53_06627 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | Hypothetical protein; COG1082 Sugar phosphate isomerases/epimerases. | 0.581 |
| EAQ05902.1 | EAQ06790.1 | SKA53_07351 | SKA53_14621 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit. | 0.906 |
| EAQ05902.1 | EAQ07066.1 | SKA53_07351 | SKA53_01681 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit. | 0.916 |
| EAQ05902.1 | EAQ07315.1 | SKA53_07351 | SKA53_02926 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits. | 0.889 |
| EAQ05902.1 | sucC | SKA53_07351 | SKA53_14531 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.869 |
| EAQ05902.1 | sucD | SKA53_07351 | SKA53_14526 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | Succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.846 |
| EAQ06790.1 | EAQ05758.1 | SKA53_14621 | SKA53_06627 | COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit. | Hypothetical protein; COG1082 Sugar phosphate isomerases/epimerases. | 0.918 |
| EAQ06790.1 | EAQ05902.1 | SKA53_14621 | SKA53_07351 | COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit. | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | 0.906 |
| EAQ06790.1 | EAQ06792.1 | SKA53_14621 | SKA53_14631 | COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit. | Alcohol dehydrogenase; COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases. | 0.930 |
| EAQ06790.1 | EAQ07066.1 | SKA53_14621 | SKA53_01681 | COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit. | COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit. | 0.998 |
| EAQ06790.1 | EAQ07315.1 | SKA53_14621 | SKA53_02926 | COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit. | COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits. | 0.904 |
| EAQ06790.1 | EAQ07780.1 | SKA53_14621 | SKA53_13123 | COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit. | COG1960 Acyl-CoA dehydrogenases. | 0.908 |
| EAQ06790.1 | EAQ07940.1 | SKA53_14621 | SKA53_09459 | COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit. | ATPase; COG1703 putative periplasmic protein kinase ArgK and related GTPases of G3E family. | 0.999 |
