| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAQ05900.1 | EAQ06794.1 | SKA53_07341 | SKA53_14641 | Putative uvrD/DNA Helicase II; COG0210 Superfamily I DNA and RNA helicases. | ATPase; COG0507 ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member. | 0.837 |
| EAQ05900.1 | EAQ07549.1 | SKA53_07341 | SKA53_11968 | Putative uvrD/DNA Helicase II; COG0210 Superfamily I DNA and RNA helicases. | ATP-dependent DNA helicase, UvrD/Rep family; COG1074 ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains); Belongs to the helicase family. UvrD subfamily. | 0.874 |
| EAQ05900.1 | EAQ07676.1 | SKA53_07341 | SKA53_12603 | Putative uvrD/DNA Helicase II; COG0210 Superfamily I DNA and RNA helicases. | COG0514 Superfamily II DNA helicase. | 0.946 |
| EAQ05900.1 | EAQ08157.1 | SKA53_07341 | SKA53_10544 | Putative uvrD/DNA Helicase II; COG0210 Superfamily I DNA and RNA helicases. | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.907 |
| EAQ05900.1 | recA | SKA53_07341 | SKA53_03339 | Putative uvrD/DNA Helicase II; COG0210 Superfamily I DNA and RNA helicases. | Recombinase A; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.906 |
| EAQ05900.1 | topA | SKA53_07341 | SKA53_08441 | Putative uvrD/DNA Helicase II; COG0210 Superfamily I DNA and RNA helicases. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.932 |
| EAQ06792.1 | EAQ06794.1 | SKA53_14631 | SKA53_14641 | Alcohol dehydrogenase; COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases. | ATPase; COG0507 ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member. | 0.831 |
| EAQ06792.1 | EAQ06795.1 | SKA53_14631 | SKA53_14646 | Alcohol dehydrogenase; COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases. | Oxidoreductase, short chain dehydrogenase/reductase family; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.751 |
| EAQ06794.1 | EAQ05900.1 | SKA53_14641 | SKA53_07341 | ATPase; COG0507 ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member. | Putative uvrD/DNA Helicase II; COG0210 Superfamily I DNA and RNA helicases. | 0.837 |
| EAQ06794.1 | EAQ06792.1 | SKA53_14641 | SKA53_14631 | ATPase; COG0507 ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member. | Alcohol dehydrogenase; COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases. | 0.831 |
| EAQ06794.1 | EAQ06795.1 | SKA53_14641 | SKA53_14646 | ATPase; COG0507 ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member. | Oxidoreductase, short chain dehydrogenase/reductase family; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.792 |
| EAQ06794.1 | EAQ06922.1 | SKA53_14641 | SKA53_15281 | ATPase; COG0507 ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member. | Hypothetical protein. | 0.773 |
| EAQ06794.1 | EAQ07281.1 | SKA53_14641 | SKA53_02756 | ATPase; COG0507 ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member. | COG1426 Uncharacterized protein conserved in bacteria. | 0.766 |
| EAQ06794.1 | EAQ07549.1 | SKA53_14641 | SKA53_11968 | ATPase; COG0507 ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member. | ATP-dependent DNA helicase, UvrD/Rep family; COG1074 ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains); Belongs to the helicase family. UvrD subfamily. | 0.947 |
| EAQ06794.1 | EAQ07676.1 | SKA53_14641 | SKA53_12603 | ATPase; COG0507 ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member. | COG0514 Superfamily II DNA helicase. | 0.882 |
| EAQ06794.1 | EAQ08157.1 | SKA53_14641 | SKA53_10544 | ATPase; COG0507 ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member. | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.903 |
| EAQ06794.1 | recA | SKA53_14641 | SKA53_03339 | ATPase; COG0507 ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member. | Recombinase A; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.782 |
| EAQ06794.1 | topA | SKA53_14641 | SKA53_08441 | ATPase; COG0507 ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.833 |
| EAQ06795.1 | EAQ06792.1 | SKA53_14646 | SKA53_14631 | Oxidoreductase, short chain dehydrogenase/reductase family; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family. | Alcohol dehydrogenase; COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases. | 0.751 |
| EAQ06795.1 | EAQ06794.1 | SKA53_14646 | SKA53_14641 | Oxidoreductase, short chain dehydrogenase/reductase family; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family. | ATPase; COG0507 ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member. | 0.792 |