| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAQ05890.1 | mrdB | SKA53_07291 | SKA53_09039 | COG0768 Cell division protein FtsI/penicillin-binding protein 2. | Rod shape-determining protein MreD; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. | 0.980 |
| EAQ05890.1 | murA | SKA53_07291 | SKA53_07646 | COG0768 Cell division protein FtsI/penicillin-binding protein 2. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.763 |
| EAQ05890.1 | murC | SKA53_07291 | SKA53_07251 | COG0768 Cell division protein FtsI/penicillin-binding protein 2. | UDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.846 |
| EAQ05890.1 | murJ | SKA53_07291 | SKA53_14726 | COG0768 Cell division protein FtsI/penicillin-binding protein 2. | Putative virulence factor, MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. | 0.678 |
| EAQ06603.1 | murJ | SKA53_13686 | SKA53_14726 | Hypothetical protein; COG1716 FOG: FHA domain. | Putative virulence factor, MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. | 0.843 |
| EAQ06813.1 | EAQ06815.1 | SKA53_14736 | SKA53_14746 | Hypothetical protein; COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component. | Hypothetical protein; COG0792 Predicted endonuclease distantly related to archaeal Holliday junction resolvase; Belongs to the UPF0102 family. | 0.756 |
| EAQ06813.1 | glnD | SKA53_14736 | SKA53_14731 | Hypothetical protein; COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component. | PII uridylyl-transferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism. | 0.855 |
| EAQ06813.1 | murJ | SKA53_14736 | SKA53_14726 | Hypothetical protein; COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component. | Putative virulence factor, MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. | 0.814 |
| EAQ06813.1 | rsmI | SKA53_14736 | SKA53_14741 | Hypothetical protein; COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component. | Hypothetical protein; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. | 0.749 |
| EAQ06815.1 | EAQ06813.1 | SKA53_14746 | SKA53_14736 | Hypothetical protein; COG0792 Predicted endonuclease distantly related to archaeal Holliday junction resolvase; Belongs to the UPF0102 family. | Hypothetical protein; COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component. | 0.756 |
| EAQ06815.1 | glnD | SKA53_14746 | SKA53_14731 | Hypothetical protein; COG0792 Predicted endonuclease distantly related to archaeal Holliday junction resolvase; Belongs to the UPF0102 family. | PII uridylyl-transferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism. | 0.707 |
| EAQ06815.1 | murJ | SKA53_14746 | SKA53_14726 | Hypothetical protein; COG0792 Predicted endonuclease distantly related to archaeal Holliday junction resolvase; Belongs to the UPF0102 family. | Putative virulence factor, MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. | 0.681 |
| EAQ06815.1 | rsmI | SKA53_14746 | SKA53_14741 | Hypothetical protein; COG0792 Predicted endonuclease distantly related to archaeal Holliday junction resolvase; Belongs to the UPF0102 family. | Hypothetical protein; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. | 0.855 |
| EAQ07715.1 | murJ | SKA53_12798 | SKA53_14726 | Mannose-6-phosphate isomerase /; COG0836 Mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family. | Putative virulence factor, MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. | 0.634 |
| glnD | EAQ06813.1 | SKA53_14731 | SKA53_14736 | PII uridylyl-transferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism. | Hypothetical protein; COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component. | 0.855 |
| glnD | EAQ06815.1 | SKA53_14731 | SKA53_14746 | PII uridylyl-transferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism. | Hypothetical protein; COG0792 Predicted endonuclease distantly related to archaeal Holliday junction resolvase; Belongs to the UPF0102 family. | 0.707 |
| glnD | murJ | SKA53_14731 | SKA53_14726 | PII uridylyl-transferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism. | Putative virulence factor, MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. | 0.866 |
| glnD | rsmI | SKA53_14731 | SKA53_14741 | PII uridylyl-transferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism. | Hypothetical protein; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. | 0.707 |
| mrdB | EAQ05890.1 | SKA53_09039 | SKA53_07291 | Rod shape-determining protein MreD; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. | COG0768 Cell division protein FtsI/penicillin-binding protein 2. | 0.980 |
| mrdB | murA | SKA53_09039 | SKA53_07646 | Rod shape-determining protein MreD; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.816 |