| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAQ06813.1 | EAQ06815.1 | SKA53_14736 | SKA53_14746 | Hypothetical protein; COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component. | Hypothetical protein; COG0792 Predicted endonuclease distantly related to archaeal Holliday junction resolvase; Belongs to the UPF0102 family. | 0.756 |
| EAQ06813.1 | glnD | SKA53_14736 | SKA53_14731 | Hypothetical protein; COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component. | PII uridylyl-transferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism. | 0.855 |
| EAQ06813.1 | gshB | SKA53_14736 | SKA53_14751 | Hypothetical protein; COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component. | COG0189 Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase); Belongs to the prokaryotic GSH synthase family. | 0.620 |
| EAQ06813.1 | murJ | SKA53_14736 | SKA53_14726 | Hypothetical protein; COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component. | Putative virulence factor, MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. | 0.814 |
| EAQ06813.1 | rsmI | SKA53_14736 | SKA53_14741 | Hypothetical protein; COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component. | Hypothetical protein; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. | 0.749 |
| EAQ06815.1 | EAQ06813.1 | SKA53_14746 | SKA53_14736 | Hypothetical protein; COG0792 Predicted endonuclease distantly related to archaeal Holliday junction resolvase; Belongs to the UPF0102 family. | Hypothetical protein; COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component. | 0.756 |
| EAQ06815.1 | EAQ07100.1 | SKA53_14746 | SKA53_01851 | Hypothetical protein; COG0792 Predicted endonuclease distantly related to archaeal Holliday junction resolvase; Belongs to the UPF0102 family. | Transcriptional regulator, MarR family; COG1846 Transcriptional regulators. | 0.485 |
| EAQ06815.1 | EAQ07166.1 | SKA53_14746 | SKA53_02181 | Hypothetical protein; COG0792 Predicted endonuclease distantly related to archaeal Holliday junction resolvase; Belongs to the UPF0102 family. | Possible flagellar switch protein FliM; COG0477 Permeases of the major facilitator superfamily. | 0.501 |
| EAQ06815.1 | glnD | SKA53_14746 | SKA53_14731 | Hypothetical protein; COG0792 Predicted endonuclease distantly related to archaeal Holliday junction resolvase; Belongs to the UPF0102 family. | PII uridylyl-transferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism. | 0.707 |
| EAQ06815.1 | gshB | SKA53_14746 | SKA53_14751 | Hypothetical protein; COG0792 Predicted endonuclease distantly related to archaeal Holliday junction resolvase; Belongs to the UPF0102 family. | COG0189 Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase); Belongs to the prokaryotic GSH synthase family. | 0.728 |
| EAQ06815.1 | murJ | SKA53_14746 | SKA53_14726 | Hypothetical protein; COG0792 Predicted endonuclease distantly related to archaeal Holliday junction resolvase; Belongs to the UPF0102 family. | Putative virulence factor, MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. | 0.681 |
| EAQ06815.1 | rsmI | SKA53_14746 | SKA53_14741 | Hypothetical protein; COG0792 Predicted endonuclease distantly related to archaeal Holliday junction resolvase; Belongs to the UPF0102 family. | Hypothetical protein; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. | 0.855 |
| EAQ07100.1 | EAQ06815.1 | SKA53_01851 | SKA53_14746 | Transcriptional regulator, MarR family; COG1846 Transcriptional regulators. | Hypothetical protein; COG0792 Predicted endonuclease distantly related to archaeal Holliday junction resolvase; Belongs to the UPF0102 family. | 0.485 |
| EAQ07100.1 | EAQ07166.1 | SKA53_01851 | SKA53_02181 | Transcriptional regulator, MarR family; COG1846 Transcriptional regulators. | Possible flagellar switch protein FliM; COG0477 Permeases of the major facilitator superfamily. | 0.505 |
| EAQ07166.1 | EAQ06815.1 | SKA53_02181 | SKA53_14746 | Possible flagellar switch protein FliM; COG0477 Permeases of the major facilitator superfamily. | Hypothetical protein; COG0792 Predicted endonuclease distantly related to archaeal Holliday junction resolvase; Belongs to the UPF0102 family. | 0.501 |
| EAQ07166.1 | EAQ07100.1 | SKA53_02181 | SKA53_01851 | Possible flagellar switch protein FliM; COG0477 Permeases of the major facilitator superfamily. | Transcriptional regulator, MarR family; COG1846 Transcriptional regulators. | 0.505 |
| glnD | EAQ06813.1 | SKA53_14731 | SKA53_14736 | PII uridylyl-transferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism. | Hypothetical protein; COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component. | 0.855 |
| glnD | EAQ06815.1 | SKA53_14731 | SKA53_14746 | PII uridylyl-transferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism. | Hypothetical protein; COG0792 Predicted endonuclease distantly related to archaeal Holliday junction resolvase; Belongs to the UPF0102 family. | 0.707 |
| glnD | gshB | SKA53_14731 | SKA53_14751 | PII uridylyl-transferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism. | COG0189 Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase); Belongs to the prokaryotic GSH synthase family. | 0.602 |
| glnD | murJ | SKA53_14731 | SKA53_14726 | PII uridylyl-transferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism. | Putative virulence factor, MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. | 0.866 |