| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAQ05273.1 | EAQ06826.1 | SKA53_05840 | SKA53_14801 | Possible transcriptional activator; COG2771 DNA-binding HTH domain-containing proteins. | Cation efflux family protein; COG0053 Predicted Co/Zn/Cd cation transporters; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. | 0.435 |
| EAQ05791.1 | EAQ06826.1 | SKA53_06792 | SKA53_14801 | Transcriptional regulator/arsenate reductase; COG0640 Predicted transcriptional regulators; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. | Cation efflux family protein; COG0053 Predicted Co/Zn/Cd cation transporters; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. | 0.416 |
| EAQ05845.1 | EAQ06826.1 | SKA53_07062 | SKA53_14801 | Dihydropteroate synthase, DHPS; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Cation efflux family protein; COG0053 Predicted Co/Zn/Cd cation transporters; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. | 0.445 |
| EAQ05845.1 | EAQ07769.1 | SKA53_07062 | SKA53_13068 | Dihydropteroate synthase, DHPS; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase. | 0.998 |
| EAQ05845.1 | EAQ08212.1 | SKA53_07062 | SKA53_10819 | Dihydropteroate synthase, DHPS; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Glutamine-pyruvate aminotransferase; COG0067 Glutamate synthase domain 1. | 0.414 |
| EAQ06826.1 | EAQ05273.1 | SKA53_14801 | SKA53_05840 | Cation efflux family protein; COG0053 Predicted Co/Zn/Cd cation transporters; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. | Possible transcriptional activator; COG2771 DNA-binding HTH domain-containing proteins. | 0.435 |
| EAQ06826.1 | EAQ05791.1 | SKA53_14801 | SKA53_06792 | Cation efflux family protein; COG0053 Predicted Co/Zn/Cd cation transporters; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. | Transcriptional regulator/arsenate reductase; COG0640 Predicted transcriptional regulators; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. | 0.416 |
| EAQ06826.1 | EAQ05845.1 | SKA53_14801 | SKA53_07062 | Cation efflux family protein; COG0053 Predicted Co/Zn/Cd cation transporters; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. | Dihydropteroate synthase, DHPS; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.445 |
| EAQ06826.1 | EAQ06827.1 | SKA53_14801 | SKA53_14806 | Cation efflux family protein; COG0053 Predicted Co/Zn/Cd cation transporters; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. | COG3807 Uncharacterized protein conserved in bacteria. | 0.761 |
| EAQ06826.1 | EAQ06828.1 | SKA53_14801 | SKA53_14811 | Cation efflux family protein; COG0053 Predicted Co/Zn/Cd cation transporters; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. | COG1052 Lactate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.504 |
| EAQ06826.1 | EAQ07445.1 | SKA53_14801 | SKA53_11448 | Cation efflux family protein; COG0053 Predicted Co/Zn/Cd cation transporters; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. | COG4787 Flagellar basal body rod protein. | 0.529 |
| EAQ06826.1 | EAQ07769.1 | SKA53_14801 | SKA53_13068 | Cation efflux family protein; COG0053 Predicted Co/Zn/Cd cation transporters; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase. | 0.445 |
| EAQ06826.1 | EAQ08212.1 | SKA53_14801 | SKA53_10819 | Cation efflux family protein; COG0053 Predicted Co/Zn/Cd cation transporters; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. | Glutamine-pyruvate aminotransferase; COG0067 Glutamate synthase domain 1. | 0.530 |
| EAQ06826.1 | mdh | SKA53_14801 | SKA53_14541 | Cation efflux family protein; COG0053 Predicted Co/Zn/Cd cation transporters; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. | 0.817 |
| EAQ06826.1 | nadE | SKA53_14801 | SKA53_08994 | Cation efflux family protein; COG0053 Predicted Co/Zn/Cd cation transporters; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. | NAD(+) synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.400 |
| EAQ06827.1 | EAQ06826.1 | SKA53_14806 | SKA53_14801 | COG3807 Uncharacterized protein conserved in bacteria. | Cation efflux family protein; COG0053 Predicted Co/Zn/Cd cation transporters; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. | 0.761 |
| EAQ06827.1 | EAQ06828.1 | SKA53_14806 | SKA53_14811 | COG3807 Uncharacterized protein conserved in bacteria. | COG1052 Lactate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.607 |
| EAQ06828.1 | EAQ06826.1 | SKA53_14811 | SKA53_14801 | COG1052 Lactate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Cation efflux family protein; COG0053 Predicted Co/Zn/Cd cation transporters; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. | 0.504 |
| EAQ06828.1 | EAQ06827.1 | SKA53_14811 | SKA53_14806 | COG1052 Lactate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | COG3807 Uncharacterized protein conserved in bacteria. | 0.607 |
| EAQ06828.1 | mdh | SKA53_14811 | SKA53_14541 | COG1052 Lactate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. | 0.514 |