| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAQ05212.1 | EAQ05916.1 | SKA53_03314 | SKA53_07421 | MetF-like protein; COG0685 5,10-methylenetetrahydrofolate reductase. | COG2873 O-acetylhomoserine sulfhydrylase. | 0.432 |
| EAQ05212.1 | EAQ06931.1 | SKA53_03314 | SKA53_15326 | MetF-like protein; COG0685 5,10-methylenetetrahydrofolate reductase. | COG0685 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | 0.907 |
| EAQ05212.1 | EAQ06946.1 | SKA53_03314 | SKA53_15401 | MetF-like protein; COG0685 5,10-methylenetetrahydrofolate reductase. | Probable 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.995 |
| EAQ05212.1 | EAQ07104.1 | SKA53_03314 | SKA53_01871 | MetF-like protein; COG0685 5,10-methylenetetrahydrofolate reductase. | COG0460 Homoserine dehydrogenase. | 0.710 |
| EAQ05212.1 | EAQ08104.1 | SKA53_03314 | SKA53_10279 | MetF-like protein; COG0685 5,10-methylenetetrahydrofolate reductase. | COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases. | 0.750 |
| EAQ05212.1 | ahcY | SKA53_03314 | SKA53_11523 | MetF-like protein; COG0685 5,10-methylenetetrahydrofolate reductase. | S-adenosyl-L-homocysteine hydrolase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.524 |
| EAQ05212.1 | fhs | SKA53_03314 | SKA53_08541 | MetF-like protein; COG0685 5,10-methylenetetrahydrofolate reductase. | Formate--tetrahydrofolate ligase; COG2759 Formyltetrahydrofolate synthetase; Belongs to the formate--tetrahydrofolate ligase family. | 0.493 |
| EAQ05212.1 | metK | SKA53_03314 | SKA53_01171 | MetF-like protein; COG0685 5,10-methylenetetrahydrofolate reductase. | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.772 |
| EAQ05212.1 | metZ | SKA53_03314 | SKA53_02111 | MetF-like protein; COG0685 5,10-methylenetetrahydrofolate reductase. | O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. | 0.750 |
| EAQ05916.1 | EAQ05212.1 | SKA53_07421 | SKA53_03314 | COG2873 O-acetylhomoserine sulfhydrylase. | MetF-like protein; COG0685 5,10-methylenetetrahydrofolate reductase. | 0.432 |
| EAQ05916.1 | EAQ06931.1 | SKA53_07421 | SKA53_15326 | COG2873 O-acetylhomoserine sulfhydrylase. | COG0685 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | 0.458 |
| EAQ05916.1 | EAQ06946.1 | SKA53_07421 | SKA53_15401 | COG2873 O-acetylhomoserine sulfhydrylase. | Probable 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.964 |
| EAQ05916.1 | EAQ07104.1 | SKA53_07421 | SKA53_01871 | COG2873 O-acetylhomoserine sulfhydrylase. | COG0460 Homoserine dehydrogenase. | 0.906 |
| EAQ05916.1 | EAQ08046.1 | SKA53_07421 | SKA53_09989 | COG2873 O-acetylhomoserine sulfhydrylase. | Aminotransferase, classes I and II; COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities. | 0.896 |
| EAQ05916.1 | EAQ08104.1 | SKA53_07421 | SKA53_10279 | COG2873 O-acetylhomoserine sulfhydrylase. | COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases. | 0.855 |
| EAQ05916.1 | ahcY | SKA53_07421 | SKA53_11523 | COG2873 O-acetylhomoserine sulfhydrylase. | S-adenosyl-L-homocysteine hydrolase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.877 |
| EAQ05916.1 | metZ | SKA53_07421 | SKA53_02111 | COG2873 O-acetylhomoserine sulfhydrylase. | O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. | 0.838 |
| EAQ06931.1 | EAQ05212.1 | SKA53_15326 | SKA53_03314 | COG0685 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | MetF-like protein; COG0685 5,10-methylenetetrahydrofolate reductase. | 0.907 |
| EAQ06931.1 | EAQ05916.1 | SKA53_15326 | SKA53_07421 | COG0685 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | COG2873 O-acetylhomoserine sulfhydrylase. | 0.458 |
| EAQ06931.1 | EAQ06946.1 | SKA53_15326 | SKA53_15401 | COG0685 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | Probable 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.998 |