node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EAP88819.1 | EAP88937.1 | OA2633_14890 | OA2633_01274 | Putative DnaJ/CbpA-type protein; COG2214 DnaJ-class molecular chaperone. | ATP-dependent Clp protease, ATP-binding subunit ClpA; COG0542 ATPases with chaperone activity, ATP-binding subunit; Belongs to the ClpA/ClpB family. | 0.707 |
EAP88819.1 | clpP | OA2633_14890 | OA2633_02991 | Putative DnaJ/CbpA-type protein; COG2214 DnaJ-class molecular chaperone. | ATP-dependent Clp protease, proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.403 |
EAP88819.1 | clpP-2 | OA2633_14890 | OA2633_04541 | Putative DnaJ/CbpA-type protein; COG2214 DnaJ-class molecular chaperone. | Hypothetical protein; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.403 |
EAP88819.1 | dnaK | OA2633_14890 | OA2633_10524 | Putative DnaJ/CbpA-type protein; COG2214 DnaJ-class molecular chaperone. | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.997 |
EAP88819.1 | groEL | OA2633_14890 | OA2633_05927 | Putative DnaJ/CbpA-type protein; COG2214 DnaJ-class molecular chaperone. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.802 |
EAP88819.1 | grpE | OA2633_14890 | OA2633_10489 | Putative DnaJ/CbpA-type protein; COG2214 DnaJ-class molecular chaperone. | Hypothetical protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dep [...] | 0.913 |
EAP88819.1 | hrcA | OA2633_14890 | OA2633_10484 | Putative DnaJ/CbpA-type protein; COG2214 DnaJ-class molecular chaperone. | Heat-inducible transcription repressor; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.644 |
EAP88937.1 | EAP88819.1 | OA2633_01274 | OA2633_14890 | ATP-dependent Clp protease, ATP-binding subunit ClpA; COG0542 ATPases with chaperone activity, ATP-binding subunit; Belongs to the ClpA/ClpB family. | Putative DnaJ/CbpA-type protein; COG2214 DnaJ-class molecular chaperone. | 0.707 |
EAP88937.1 | EAP89922.1 | OA2633_01274 | OA2633_06909 | ATP-dependent Clp protease, ATP-binding subunit ClpA; COG0542 ATPases with chaperone activity, ATP-binding subunit; Belongs to the ClpA/ClpB family. | DnaJ-related protein; COG2214 DnaJ-class molecular chaperone. | 0.668 |
EAP88937.1 | clpP | OA2633_01274 | OA2633_02991 | ATP-dependent Clp protease, ATP-binding subunit ClpA; COG0542 ATPases with chaperone activity, ATP-binding subunit; Belongs to the ClpA/ClpB family. | ATP-dependent Clp protease, proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.953 |
EAP88937.1 | clpP-2 | OA2633_01274 | OA2633_04541 | ATP-dependent Clp protease, ATP-binding subunit ClpA; COG0542 ATPases with chaperone activity, ATP-binding subunit; Belongs to the ClpA/ClpB family. | Hypothetical protein; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.955 |
EAP88937.1 | dnaJ | OA2633_01274 | OA2633_10529 | ATP-dependent Clp protease, ATP-binding subunit ClpA; COG0542 ATPases with chaperone activity, ATP-binding subunit; Belongs to the ClpA/ClpB family. | Chaperone, DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and [...] | 0.704 |
EAP88937.1 | dnaK | OA2633_01274 | OA2633_10524 | ATP-dependent Clp protease, ATP-binding subunit ClpA; COG0542 ATPases with chaperone activity, ATP-binding subunit; Belongs to the ClpA/ClpB family. | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.977 |
EAP88937.1 | groEL | OA2633_01274 | OA2633_05927 | ATP-dependent Clp protease, ATP-binding subunit ClpA; COG0542 ATPases with chaperone activity, ATP-binding subunit; Belongs to the ClpA/ClpB family. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.648 |
EAP88937.1 | grpE | OA2633_01274 | OA2633_10489 | ATP-dependent Clp protease, ATP-binding subunit ClpA; COG0542 ATPases with chaperone activity, ATP-binding subunit; Belongs to the ClpA/ClpB family. | Hypothetical protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dep [...] | 0.803 |
EAP88937.1 | hrcA | OA2633_01274 | OA2633_10484 | ATP-dependent Clp protease, ATP-binding subunit ClpA; COG0542 ATPases with chaperone activity, ATP-binding subunit; Belongs to the ClpA/ClpB family. | Heat-inducible transcription repressor; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.604 |
EAP89922.1 | EAP88937.1 | OA2633_06909 | OA2633_01274 | DnaJ-related protein; COG2214 DnaJ-class molecular chaperone. | ATP-dependent Clp protease, ATP-binding subunit ClpA; COG0542 ATPases with chaperone activity, ATP-binding subunit; Belongs to the ClpA/ClpB family. | 0.668 |
EAP89922.1 | dnaK | OA2633_06909 | OA2633_10524 | DnaJ-related protein; COG2214 DnaJ-class molecular chaperone. | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.985 |
EAP89922.1 | groEL | OA2633_06909 | OA2633_05927 | DnaJ-related protein; COG2214 DnaJ-class molecular chaperone. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.713 |
EAP89922.1 | grpE | OA2633_06909 | OA2633_10489 | DnaJ-related protein; COG2214 DnaJ-class molecular chaperone. | Hypothetical protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dep [...] | 0.767 |