| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAR49766.1 | EAR50868.1 | OG2516_04693 | OG2516_00155 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | COG1092 Predicted SAM-dependent methyltransferases. | 0.457 |
| EAR49766.1 | EAR51723.1 | OG2516_04693 | OG2516_06656 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Hypothetical protein; COG0840 Methyl-accepting chemotaxis protein. | 0.598 |
| EAR49766.1 | polA | OG2516_04693 | OG2516_16856 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.648 |
| EAR50416.1 | EAR50868.1 | OG2516_02833 | OG2516_00155 | COG0595 Predicted hydrolase of the metallo-beta-lactamase superfamily. | COG1092 Predicted SAM-dependent methyltransferases. | 0.446 |
| EAR50866.1 | EAR50868.1 | OG2516_00145 | OG2516_00155 | KDPG/KHG bifunctional aldolase; COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase. | COG1092 Predicted SAM-dependent methyltransferases. | 0.457 |
| EAR50866.1 | EAR50869.1 | OG2516_00145 | OG2516_00160 | KDPG/KHG bifunctional aldolase; COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase. | Hypothetical protein. | 0.454 |
| EAR50866.1 | edd | OG2516_00145 | OG2516_00150 | KDPG/KHG bifunctional aldolase; COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase. | Phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. | 0.998 |
| EAR50868.1 | EAR49766.1 | OG2516_00155 | OG2516_04693 | COG1092 Predicted SAM-dependent methyltransferases. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.457 |
| EAR50868.1 | EAR50416.1 | OG2516_00155 | OG2516_02833 | COG1092 Predicted SAM-dependent methyltransferases. | COG0595 Predicted hydrolase of the metallo-beta-lactamase superfamily. | 0.446 |
| EAR50868.1 | EAR50866.1 | OG2516_00155 | OG2516_00145 | COG1092 Predicted SAM-dependent methyltransferases. | KDPG/KHG bifunctional aldolase; COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase. | 0.457 |
| EAR50868.1 | EAR50869.1 | OG2516_00155 | OG2516_00160 | COG1092 Predicted SAM-dependent methyltransferases. | Hypothetical protein. | 0.855 |
| EAR50868.1 | EAR51395.1 | OG2516_00155 | OG2516_15564 | COG1092 Predicted SAM-dependent methyltransferases. | RNA pseudouridine synthase family protein; COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases; Belongs to the pseudouridine synthase RsuA family. | 0.485 |
| EAR50868.1 | EAR51723.1 | OG2516_00155 | OG2516_06656 | COG1092 Predicted SAM-dependent methyltransferases. | Hypothetical protein; COG0840 Methyl-accepting chemotaxis protein. | 0.418 |
| EAR50868.1 | dut | OG2516_00155 | OG2516_13706 | COG1092 Predicted SAM-dependent methyltransferases. | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.427 |
| EAR50868.1 | edd | OG2516_00155 | OG2516_00150 | COG1092 Predicted SAM-dependent methyltransferases. | Phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. | 0.666 |
| EAR50868.1 | gcvP | OG2516_00155 | OG2516_14945 | COG1092 Predicted SAM-dependent methyltransferases. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.412 |
| EAR50868.1 | polA | OG2516_00155 | OG2516_16856 | COG1092 Predicted SAM-dependent methyltransferases. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.412 |
| EAR50869.1 | EAR50866.1 | OG2516_00160 | OG2516_00145 | Hypothetical protein. | KDPG/KHG bifunctional aldolase; COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase. | 0.454 |
| EAR50869.1 | EAR50868.1 | OG2516_00160 | OG2516_00155 | Hypothetical protein. | COG1092 Predicted SAM-dependent methyltransferases. | 0.855 |
| EAR50869.1 | EAR51723.1 | OG2516_00160 | OG2516_06656 | Hypothetical protein. | Hypothetical protein; COG0840 Methyl-accepting chemotaxis protein. | 0.528 |