| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAR49583.1 | EAR49585.1 | OG2516_09103 | OG2516_09113 | Precorrin-3B C17-methyltransferase region protein; COG2073 Cobalamin biosynthesis protein CbiG. | CobL, precorrin-6Y C5,15-methyltransferase; COG2241 Precorrin-6B methylase 1. | 0.999 |
| EAR49583.1 | EAR51636.1 | OG2516_09103 | OG2516_03590 | Precorrin-3B C17-methyltransferase region protein; COG2073 Cobalamin biosynthesis protein CbiG. | Probable uroporphyrin-iii c-methyltransferase protein; COG0007 Uroporphyrinogen-III methylase; Belongs to the precorrin methyltransferase family. | 0.954 |
| EAR49583.1 | EAR52791.1 | OG2516_09103 | OG2516_01154 | Precorrin-3B C17-methyltransferase region protein; COG2073 Cobalamin biosynthesis protein CbiG. | COG0155 Sulfite reductase, beta subunit (hemoprotein). | 0.934 |
| EAR49583.1 | EAR52793.1 | OG2516_09103 | OG2516_01164 | Precorrin-3B C17-methyltransferase region protein; COG2073 Cobalamin biosynthesis protein CbiG. | uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | 0.957 |
| EAR49585.1 | EAR49583.1 | OG2516_09113 | OG2516_09103 | CobL, precorrin-6Y C5,15-methyltransferase; COG2241 Precorrin-6B methylase 1. | Precorrin-3B C17-methyltransferase region protein; COG2073 Cobalamin biosynthesis protein CbiG. | 0.999 |
| EAR49585.1 | EAR51636.1 | OG2516_09113 | OG2516_03590 | CobL, precorrin-6Y C5,15-methyltransferase; COG2241 Precorrin-6B methylase 1. | Probable uroporphyrin-iii c-methyltransferase protein; COG0007 Uroporphyrinogen-III methylase; Belongs to the precorrin methyltransferase family. | 0.688 |
| EAR49585.1 | EAR52791.1 | OG2516_09113 | OG2516_01154 | CobL, precorrin-6Y C5,15-methyltransferase; COG2241 Precorrin-6B methylase 1. | COG0155 Sulfite reductase, beta subunit (hemoprotein). | 0.927 |
| EAR49585.1 | EAR52793.1 | OG2516_09113 | OG2516_01164 | CobL, precorrin-6Y C5,15-methyltransferase; COG2241 Precorrin-6B methylase 1. | uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | 0.947 |
| EAR50149.1 | EAR52790.1 | OG2516_15714 | OG2516_01149 | Iron-sulfur cluster-binding protein; COG0633 Ferredoxin. | Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily. | 0.450 |
| EAR50149.1 | EAR52791.1 | OG2516_15714 | OG2516_01154 | Iron-sulfur cluster-binding protein; COG0633 Ferredoxin. | COG0155 Sulfite reductase, beta subunit (hemoprotein). | 0.951 |
| EAR51057.1 | EAR52790.1 | OG2516_04144 | OG2516_01149 | Molybdopterin oxidoreductase; COG2041 Sulfite oxidase and related enzymes. | Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily. | 0.907 |
| EAR51057.1 | EAR52791.1 | OG2516_04144 | OG2516_01154 | Molybdopterin oxidoreductase; COG2041 Sulfite oxidase and related enzymes. | COG0155 Sulfite reductase, beta subunit (hemoprotein). | 0.911 |
| EAR51057.1 | cysC | OG2516_04144 | OG2516_13981 | Molybdopterin oxidoreductase; COG2041 Sulfite oxidase and related enzymes. | Binfunctional sulfate adenylyltransferase subunit 1/adenylylsulfate kinase protein; Catalyzes the synthesis of activated sulfate. | 0.903 |
| EAR51375.1 | EAR52790.1 | OG2516_15464 | OG2516_01149 | Possible dioxygenase reductase subunit; COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1. | Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily. | 0.402 |
| EAR51375.1 | EAR52791.1 | OG2516_15464 | OG2516_01154 | Possible dioxygenase reductase subunit; COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1. | COG0155 Sulfite reductase, beta subunit (hemoprotein). | 0.949 |
| EAR51636.1 | EAR49583.1 | OG2516_03590 | OG2516_09103 | Probable uroporphyrin-iii c-methyltransferase protein; COG0007 Uroporphyrinogen-III methylase; Belongs to the precorrin methyltransferase family. | Precorrin-3B C17-methyltransferase region protein; COG2073 Cobalamin biosynthesis protein CbiG. | 0.954 |
| EAR51636.1 | EAR49585.1 | OG2516_03590 | OG2516_09113 | Probable uroporphyrin-iii c-methyltransferase protein; COG0007 Uroporphyrinogen-III methylase; Belongs to the precorrin methyltransferase family. | CobL, precorrin-6Y C5,15-methyltransferase; COG2241 Precorrin-6B methylase 1. | 0.688 |
| EAR51636.1 | EAR52790.1 | OG2516_03590 | OG2516_01149 | Probable uroporphyrin-iii c-methyltransferase protein; COG0007 Uroporphyrinogen-III methylase; Belongs to the precorrin methyltransferase family. | Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily. | 0.944 |
| EAR51636.1 | EAR52791.1 | OG2516_03590 | OG2516_01154 | Probable uroporphyrin-iii c-methyltransferase protein; COG0007 Uroporphyrinogen-III methylase; Belongs to the precorrin methyltransferase family. | COG0155 Sulfite reductase, beta subunit (hemoprotein). | 0.946 |
| EAR51636.1 | EAR52793.1 | OG2516_03590 | OG2516_01164 | Probable uroporphyrin-iii c-methyltransferase protein; COG0007 Uroporphyrinogen-III methylase; Belongs to the precorrin methyltransferase family. | uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | 0.985 |