| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAR49766.1 | EAR50848.1 | OG2516_04693 | OG2516_00055 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | PAS; COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain. | 0.727 |
| EAR49766.1 | EAR50849.1 | OG2516_04693 | OG2516_00060 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain. | 0.692 |
| EAR49766.1 | EAR51515.1 | OG2516_04693 | OG2516_01311 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | COG1514 2'-5' RNA ligase. | 0.407 |
| EAR49766.1 | ispDF | OG2516_04693 | OG2516_04476 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF). | 0.693 |
| EAR50848.1 | EAR49766.1 | OG2516_00055 | OG2516_04693 | PAS; COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.727 |
| EAR50848.1 | EAR50849.1 | OG2516_00055 | OG2516_00060 | PAS; COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain. | COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain. | 0.999 |
| EAR50848.1 | EAR51515.1 | OG2516_00055 | OG2516_01311 | PAS; COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain. | COG1514 2'-5' RNA ligase. | 0.419 |
| EAR50848.1 | EAR51516.1 | OG2516_00055 | OG2516_01316 | PAS; COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain. | enoyl-CoA hydratase/isomerase family protein; COG1024 Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family. | 0.985 |
| EAR50848.1 | gcvP | OG2516_00055 | OG2516_14945 | PAS; COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.693 |
| EAR50848.1 | ispDF | OG2516_00055 | OG2516_04476 | PAS; COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain. | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF). | 0.514 |
| EAR50849.1 | EAR49766.1 | OG2516_00060 | OG2516_04693 | COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.692 |
| EAR50849.1 | EAR50848.1 | OG2516_00060 | OG2516_00055 | COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain. | PAS; COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain. | 0.999 |
| EAR50849.1 | EAR51515.1 | OG2516_00060 | OG2516_01311 | COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain. | COG1514 2'-5' RNA ligase. | 0.414 |
| EAR50849.1 | EAR51516.1 | OG2516_00060 | OG2516_01316 | COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain. | enoyl-CoA hydratase/isomerase family protein; COG1024 Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family. | 0.976 |
| EAR50849.1 | gcvP | OG2516_00060 | OG2516_14945 | COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.692 |
| EAR50849.1 | ispDF | OG2516_00060 | OG2516_04476 | COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain. | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF). | 0.509 |
| EAR51515.1 | EAR49766.1 | OG2516_01311 | OG2516_04693 | COG1514 2'-5' RNA ligase. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.407 |
| EAR51515.1 | EAR50848.1 | OG2516_01311 | OG2516_00055 | COG1514 2'-5' RNA ligase. | PAS; COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain. | 0.419 |
| EAR51515.1 | EAR50849.1 | OG2516_01311 | OG2516_00060 | COG1514 2'-5' RNA ligase. | COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain. | 0.414 |
| EAR51515.1 | EAR51516.1 | OG2516_01311 | OG2516_01316 | COG1514 2'-5' RNA ligase. | enoyl-CoA hydratase/isomerase family protein; COG1024 Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family. | 0.773 |