| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAR49879.1 | EAR51626.1 | OG2516_14131 | OG2516_01866 | COG0287 Prephenate dehydrogenase. | Hypothetical protein; COG2607 Predicted ATPase (AAA+ superfamily). | 0.593 |
| EAR50613.1 | EAR51626.1 | OG2516_12216 | OG2516_01866 | Transcriptional regulator, MarR family protein; COG1846 Transcriptional regulators. | Hypothetical protein; COG2607 Predicted ATPase (AAA+ superfamily). | 0.487 |
| EAR51400.1 | EAR51626.1 | OG2516_15589 | OG2516_01866 | COG0440 Acetolactate synthase, small (regulatory) subunit. | Hypothetical protein; COG2607 Predicted ATPase (AAA+ superfamily). | 0.415 |
| EAR51400.1 | ilvC | OG2516_15589 | OG2516_07375 | COG0440 Acetolactate synthase, small (regulatory) subunit. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.998 |
| EAR51622.1 | EAR51624.1 | OG2516_01846 | OG2516_01856 | Hypothetical protein; COG2378 Predicted transcriptional regulator. | Twin-arginine translocation protein TatB; COG1826 Sec-independent protein secretion pathway components. | 0.523 |
| EAR51622.1 | EAR51626.1 | OG2516_01846 | OG2516_01866 | Hypothetical protein; COG2378 Predicted transcriptional regulator. | Hypothetical protein; COG2607 Predicted ATPase (AAA+ superfamily). | 0.523 |
| EAR51622.1 | tatA | OG2516_01846 | OG2516_01851 | Hypothetical protein; COG2378 Predicted transcriptional regulator. | Twin-arginine translocation protein, TatA/E family protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. | 0.589 |
| EAR51622.1 | tatC | OG2516_01846 | OG2516_01861 | Hypothetical protein; COG2378 Predicted transcriptional regulator. | Twin-arginine translocation system protein, TatC; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides. | 0.523 |
| EAR51624.1 | EAR51622.1 | OG2516_01856 | OG2516_01846 | Twin-arginine translocation protein TatB; COG1826 Sec-independent protein secretion pathway components. | Hypothetical protein; COG2378 Predicted transcriptional regulator. | 0.523 |
| EAR51624.1 | EAR51626.1 | OG2516_01856 | OG2516_01866 | Twin-arginine translocation protein TatB; COG1826 Sec-independent protein secretion pathway components. | Hypothetical protein; COG2607 Predicted ATPase (AAA+ superfamily). | 0.855 |
| EAR51624.1 | EAR51627.1 | OG2516_01856 | OG2516_01871 | Twin-arginine translocation protein TatB; COG1826 Sec-independent protein secretion pathway components. | RNA methyltransferase, TrmH family, group 1; COG0565 rRNA methylase. | 0.458 |
| EAR51624.1 | tatA | OG2516_01856 | OG2516_01851 | Twin-arginine translocation protein TatB; COG1826 Sec-independent protein secretion pathway components. | Twin-arginine translocation protein, TatA/E family protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. | 0.999 |
| EAR51624.1 | tatC | OG2516_01856 | OG2516_01861 | Twin-arginine translocation protein TatB; COG1826 Sec-independent protein secretion pathway components. | Twin-arginine translocation system protein, TatC; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides. | 0.999 |
| EAR51626.1 | EAR49879.1 | OG2516_01866 | OG2516_14131 | Hypothetical protein; COG2607 Predicted ATPase (AAA+ superfamily). | COG0287 Prephenate dehydrogenase. | 0.593 |
| EAR51626.1 | EAR50613.1 | OG2516_01866 | OG2516_12216 | Hypothetical protein; COG2607 Predicted ATPase (AAA+ superfamily). | Transcriptional regulator, MarR family protein; COG1846 Transcriptional regulators. | 0.487 |
| EAR51626.1 | EAR51400.1 | OG2516_01866 | OG2516_15589 | Hypothetical protein; COG2607 Predicted ATPase (AAA+ superfamily). | COG0440 Acetolactate synthase, small (regulatory) subunit. | 0.415 |
| EAR51626.1 | EAR51622.1 | OG2516_01866 | OG2516_01846 | Hypothetical protein; COG2607 Predicted ATPase (AAA+ superfamily). | Hypothetical protein; COG2378 Predicted transcriptional regulator. | 0.523 |
| EAR51626.1 | EAR51624.1 | OG2516_01866 | OG2516_01856 | Hypothetical protein; COG2607 Predicted ATPase (AAA+ superfamily). | Twin-arginine translocation protein TatB; COG1826 Sec-independent protein secretion pathway components. | 0.855 |
| EAR51626.1 | EAR51627.1 | OG2516_01866 | OG2516_01871 | Hypothetical protein; COG2607 Predicted ATPase (AAA+ superfamily). | RNA methyltransferase, TrmH family, group 1; COG0565 rRNA methylase. | 0.450 |
| EAR51626.1 | ilvC | OG2516_01866 | OG2516_07375 | Hypothetical protein; COG2607 Predicted ATPase (AAA+ superfamily). | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.587 |