| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAR50392.1 | EAR50393.1 | OG2516_02713 | OG2516_02718 | Lipocalin-related protein and Bos/Can/Equ allergen; COG0628 Predicted permease. | Hypothetical protein; COG0593 ATPase involved in DNA replication initiation; Belongs to the DnaA family. | 0.974 |
| EAR50392.1 | dnaA | OG2516_02713 | OG2516_10134 | Lipocalin-related protein and Bos/Can/Equ allergen; COG0628 Predicted permease. | Chromosomal replication initiation protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | 0.430 |
| EAR50392.1 | ppk | OG2516_02713 | OG2516_02723 | Lipocalin-related protein and Bos/Can/Equ allergen; COG0628 Predicted permease. | Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. | 0.855 |
| EAR50392.1 | recF | OG2516_02713 | OG2516_10144 | Lipocalin-related protein and Bos/Can/Equ allergen; COG0628 Predicted permease. | Recombination protein F; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. | 0.528 |
| EAR50393.1 | EAR50392.1 | OG2516_02718 | OG2516_02713 | Hypothetical protein; COG0593 ATPase involved in DNA replication initiation; Belongs to the DnaA family. | Lipocalin-related protein and Bos/Can/Equ allergen; COG0628 Predicted permease. | 0.974 |
| EAR50393.1 | EAR50755.1 | OG2516_02718 | OG2516_10139 | Hypothetical protein; COG0593 ATPase involved in DNA replication initiation; Belongs to the DnaA family. | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.998 |
| EAR50393.1 | EAR50813.1 | OG2516_02718 | OG2516_09448 | Hypothetical protein; COG0593 ATPase involved in DNA replication initiation; Belongs to the DnaA family. | COG0254 Ribosomal protein L31; Belongs to the bacterial ribosomal protein bL31 family. | 0.848 |
| EAR50393.1 | EAR51599.1 | OG2516_02718 | OG2516_01731 | Hypothetical protein; COG0593 ATPase involved in DNA replication initiation; Belongs to the DnaA family. | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | 0.939 |
| EAR50393.1 | EAR52589.1 | OG2516_02718 | OG2516_05758 | Hypothetical protein; COG0593 ATPase involved in DNA replication initiation; Belongs to the DnaA family. | COG0307 Riboflavin synthase alpha chain. | 0.750 |
| EAR50393.1 | dnaA | OG2516_02718 | OG2516_10134 | Hypothetical protein; COG0593 ATPase involved in DNA replication initiation; Belongs to the DnaA family. | Chromosomal replication initiation protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | 0.762 |
| EAR50393.1 | ppk | OG2516_02718 | OG2516_02723 | Hypothetical protein; COG0593 ATPase involved in DNA replication initiation; Belongs to the DnaA family. | Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. | 0.879 |
| EAR50393.1 | recF | OG2516_02718 | OG2516_10144 | Hypothetical protein; COG0593 ATPase involved in DNA replication initiation; Belongs to the DnaA family. | Recombination protein F; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. | 0.865 |
| EAR50393.1 | recO-2 | OG2516_02718 | OG2516_08738 | Hypothetical protein; COG0593 ATPase involved in DNA replication initiation; Belongs to the DnaA family. | DNA repair protein RecO, putative; Involved in DNA repair and RecF pathway recombination. | 0.675 |
| EAR50393.1 | rpmJ | OG2516_02718 | OG2516_09894 | Hypothetical protein; COG0593 ATPase involved in DNA replication initiation; Belongs to the DnaA family. | COG0257 Ribosomal protein L36; Belongs to the bacterial ribosomal protein bL36 family. | 0.812 |
| EAR50755.1 | EAR50393.1 | OG2516_10139 | OG2516_02718 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Hypothetical protein; COG0593 ATPase involved in DNA replication initiation; Belongs to the DnaA family. | 0.998 |
| EAR50755.1 | EAR51599.1 | OG2516_10139 | OG2516_01731 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | 0.779 |
| EAR50755.1 | dnaA | OG2516_10139 | OG2516_10134 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Chromosomal replication initiation protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | 0.999 |
| EAR50755.1 | recF | OG2516_10139 | OG2516_10144 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Recombination protein F; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. | 0.981 |
| EAR50755.1 | recO-2 | OG2516_10139 | OG2516_08738 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA repair protein RecO, putative; Involved in DNA repair and RecF pathway recombination. | 0.651 |
| EAR50813.1 | EAR50393.1 | OG2516_09448 | OG2516_02718 | COG0254 Ribosomal protein L31; Belongs to the bacterial ribosomal protein bL31 family. | Hypothetical protein; COG0593 ATPase involved in DNA replication initiation; Belongs to the DnaA family. | 0.848 |
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