| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAR49446.1 | EAR50990.1 | OG2516_18830 | OG2516_03278 | PaxA, putative; COG2931 RTX toxins and related Ca2+-binding proteins. | COG2374 Predicted extracellular nuclease. | 0.698 |
| EAR49446.1 | EAR52243.1 | OG2516_18830 | OG2516_02364 | PaxA, putative; COG2931 RTX toxins and related Ca2+-binding proteins. | Hypothetical protein; COG2931 RTX toxins and related Ca2+-binding proteins. | 0.722 |
| EAR49446.1 | guaA | OG2516_18830 | OG2516_02504 | PaxA, putative; COG2931 RTX toxins and related Ca2+-binding proteins. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.625 |
| EAR50432.1 | EAR50536.1 | OG2516_08843 | OG2516_09835 | Ser/Thr protein phosphatase/nucleotidase, putative; COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family. | 2',3'-cyclic-nucleotide 2'-phosphodiesterase; COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family. | 0.832 |
| EAR50432.1 | EAR50990.1 | OG2516_08843 | OG2516_03278 | Ser/Thr protein phosphatase/nucleotidase, putative; COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family. | COG2374 Predicted extracellular nuclease. | 0.950 |
| EAR50432.1 | EAR52037.1 | OG2516_08843 | OG2516_13469 | Ser/Thr protein phosphatase/nucleotidase, putative; COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family. | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | 0.885 |
| EAR50432.1 | cpdB | OG2516_08843 | OG2516_02579 | Ser/Thr protein phosphatase/nucleotidase, putative; COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family. | 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase bifunctional periplasmic protein; COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family. | 0.826 |
| EAR50432.1 | deoA | OG2516_08843 | OG2516_13474 | Ser/Thr protein phosphatase/nucleotidase, putative; COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family. | Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. | 0.861 |
| EAR50432.1 | guaA | OG2516_08843 | OG2516_02504 | Ser/Thr protein phosphatase/nucleotidase, putative; COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.869 |
| EAR50432.1 | tmk | OG2516_08843 | OG2516_07203 | Ser/Thr protein phosphatase/nucleotidase, putative; COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.860 |
| EAR50536.1 | EAR50432.1 | OG2516_09835 | OG2516_08843 | 2',3'-cyclic-nucleotide 2'-phosphodiesterase; COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family. | Ser/Thr protein phosphatase/nucleotidase, putative; COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family. | 0.832 |
| EAR50536.1 | EAR50990.1 | OG2516_09835 | OG2516_03278 | 2',3'-cyclic-nucleotide 2'-phosphodiesterase; COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family. | COG2374 Predicted extracellular nuclease. | 0.544 |
| EAR50536.1 | EAR52037.1 | OG2516_09835 | OG2516_13469 | 2',3'-cyclic-nucleotide 2'-phosphodiesterase; COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family. | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | 0.787 |
| EAR50536.1 | guaA | OG2516_09835 | OG2516_02504 | 2',3'-cyclic-nucleotide 2'-phosphodiesterase; COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.782 |
| EAR50990.1 | EAR49446.1 | OG2516_03278 | OG2516_18830 | COG2374 Predicted extracellular nuclease. | PaxA, putative; COG2931 RTX toxins and related Ca2+-binding proteins. | 0.698 |
| EAR50990.1 | EAR50432.1 | OG2516_03278 | OG2516_08843 | COG2374 Predicted extracellular nuclease. | Ser/Thr protein phosphatase/nucleotidase, putative; COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family. | 0.950 |
| EAR50990.1 | EAR50536.1 | OG2516_03278 | OG2516_09835 | COG2374 Predicted extracellular nuclease. | 2',3'-cyclic-nucleotide 2'-phosphodiesterase; COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family. | 0.544 |
| EAR50990.1 | EAR52037.1 | OG2516_03278 | OG2516_13469 | COG2374 Predicted extracellular nuclease. | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | 0.459 |
| EAR50990.1 | EAR52243.1 | OG2516_03278 | OG2516_02364 | COG2374 Predicted extracellular nuclease. | Hypothetical protein; COG2931 RTX toxins and related Ca2+-binding proteins. | 0.817 |
| EAR50990.1 | cpdB | OG2516_03278 | OG2516_02579 | COG2374 Predicted extracellular nuclease. | 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase bifunctional periplasmic protein; COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family. | 0.541 |