| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAR49688.1 | EAR49689.1 | OG2516_03498 | OG2516_03503 | mazG family protein; COG1694 Predicted pyrophosphatase. | ABC Fe+3 siderophore transporter, periplasmic substrate-binding protein; COG1840 ABC-type Fe3+ transport system, periplasmic component. | 0.719 |
| EAR49688.1 | EAR49690.1 | OG2516_03498 | OG2516_03508 | mazG family protein; COG1694 Predicted pyrophosphatase. | COG0598 Mg2+ and Co2+ transporters. | 0.445 |
| EAR49688.1 | EAR50848.1 | OG2516_03498 | OG2516_00055 | mazG family protein; COG1694 Predicted pyrophosphatase. | PAS; COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain. | 0.904 |
| EAR49688.1 | EAR50849.1 | OG2516_03498 | OG2516_00060 | mazG family protein; COG1694 Predicted pyrophosphatase. | COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain. | 0.822 |
| EAR49688.1 | EAR52793.1 | OG2516_03498 | OG2516_01164 | mazG family protein; COG1694 Predicted pyrophosphatase. | uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | 0.707 |
| EAR49688.1 | guaB | OG2516_03498 | OG2516_03513 | mazG family protein; COG1694 Predicted pyrophosphatase. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.862 |
| EAR49688.1 | prmC | OG2516_03498 | OG2516_03488 | mazG family protein; COG1694 Predicted pyrophosphatase. | Modification methylase, HemK family protein; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily. | 0.608 |
| EAR49689.1 | EAR49688.1 | OG2516_03503 | OG2516_03498 | ABC Fe+3 siderophore transporter, periplasmic substrate-binding protein; COG1840 ABC-type Fe3+ transport system, periplasmic component. | mazG family protein; COG1694 Predicted pyrophosphatase. | 0.719 |
| EAR49689.1 | EAR49690.1 | OG2516_03503 | OG2516_03508 | ABC Fe+3 siderophore transporter, periplasmic substrate-binding protein; COG1840 ABC-type Fe3+ transport system, periplasmic component. | COG0598 Mg2+ and Co2+ transporters. | 0.649 |
| EAR49689.1 | EAR50848.1 | OG2516_03503 | OG2516_00055 | ABC Fe+3 siderophore transporter, periplasmic substrate-binding protein; COG1840 ABC-type Fe3+ transport system, periplasmic component. | PAS; COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain. | 0.547 |
| EAR49689.1 | guaB | OG2516_03503 | OG2516_03513 | ABC Fe+3 siderophore transporter, periplasmic substrate-binding protein; COG1840 ABC-type Fe3+ transport system, periplasmic component. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.479 |
| EAR49689.1 | prmC | OG2516_03503 | OG2516_03488 | ABC Fe+3 siderophore transporter, periplasmic substrate-binding protein; COG1840 ABC-type Fe3+ transport system, periplasmic component. | Modification methylase, HemK family protein; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily. | 0.408 |
| EAR49690.1 | EAR49688.1 | OG2516_03508 | OG2516_03498 | COG0598 Mg2+ and Co2+ transporters. | mazG family protein; COG1694 Predicted pyrophosphatase. | 0.445 |
| EAR49690.1 | EAR49689.1 | OG2516_03508 | OG2516_03503 | COG0598 Mg2+ and Co2+ transporters. | ABC Fe+3 siderophore transporter, periplasmic substrate-binding protein; COG1840 ABC-type Fe3+ transport system, periplasmic component. | 0.649 |
| EAR49690.1 | EAR50848.1 | OG2516_03508 | OG2516_00055 | COG0598 Mg2+ and Co2+ transporters. | PAS; COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain. | 0.530 |
| EAR49690.1 | EAR50849.1 | OG2516_03508 | OG2516_00060 | COG0598 Mg2+ and Co2+ transporters. | COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain. | 0.425 |
| EAR49690.1 | EAR51348.1 | OG2516_03508 | OG2516_15329 | COG0598 Mg2+ and Co2+ transporters. | COG2217 Cation transport ATPase. | 0.491 |
| EAR49690.1 | EAR51684.1 | OG2516_03508 | OG2516_03830 | COG0598 Mg2+ and Co2+ transporters. | Possible ribosomal protein S6 modification protein; COG4067 Uncharacterized protein conserved in archaea. | 0.574 |
| EAR49690.1 | EAR52793.1 | OG2516_03508 | OG2516_01164 | COG0598 Mg2+ and Co2+ transporters. | uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | 0.406 |
| EAR49690.1 | EAR53009.1 | OG2516_03508 | OG2516_11116 | COG0598 Mg2+ and Co2+ transporters. | OmpA domain protein; COG0226 ABC-type phosphate transport system, periplasmic component. | 0.464 |