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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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experimentally determined
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EAR51636.1Probable uroporphyrin-iii c-methyltransferase protein; COG0007 Uroporphyrinogen-III methylase; Belongs to the precorrin methyltransferase family. (283 aa)    
Predicted Functional Partners:
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
 
 0.995
EAR49587.1
Hypothetical protein.
 
 0.983
EAR52793.1
uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
 
 
0.979
EAR49584.1
COG2243 Precorrin-2 methylase; Belongs to the precorrin methyltransferase family.
 
  
 0.977
cysC
Binfunctional sulfate adenylyltransferase subunit 1/adenylylsulfate kinase protein; Catalyzes the synthesis of activated sulfate.
 
  
 0.960
EAR49583.1
Precorrin-3B C17-methyltransferase region protein; COG2073 Cobalamin biosynthesis protein CbiG.
 
 
 0.949
EAR52265.1
COG0113 Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
 
 
 0.939
cobB
Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.
   
 0.939
EAR52791.1
COG0155 Sulfite reductase, beta subunit (hemoprotein).
 
  
 0.926
EAR52790.1
Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily.
 
  
 0.924
Your Current Organism:
Oceanicola granulosus
NCBI taxonomy Id: 314256
Other names: O. granulosus HTCC2516, Oceanicola granulosus HTCC2516, Oceanicola granulosus KCTC 12143, Oceanicola granulosus str. HTCC2516, Oceanicola granulosus strain HTCC2516
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