| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAR50080.1 | EAR52866.1 | OG2516_06404 | OG2516_10401 | Bifunctional PutA protein; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | 0.916 |
| EAR50080.1 | argD | OG2516_06404 | OG2516_14166 | Bifunctional PutA protein; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | COG4992 Ornithine/acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. | 0.919 |
| EAR50080.1 | proA | OG2516_06404 | OG2516_03964 | Bifunctional PutA protein; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | Gamma-glutamyl phosphate reductase GPR; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | 0.918 |
| EAR50080.1 | proB | OG2516_06404 | OG2516_03974 | Bifunctional PutA protein; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | Gamma-glutamyl kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. | 0.922 |
| EAR50080.1 | proC | OG2516_06404 | OG2516_14301 | Bifunctional PutA protein; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | 0.952 |
| EAR50080.1 | ribB | OG2516_06404 | OG2516_05763 | Bifunctional PutA protein; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | Bifunctional GTP cyclohydrolaseII/3,4-dihydroxy-2butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.525 |
| EAR51022.1 | obg | OG2516_03969 | OG2516_03979 | Streptomycin phosphotransferase, streptomycin-resistance; COG3570 Streptomycin 6-kinase. | GTP-binding protein, GTP1/OBG family protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 0.773 |
| EAR51022.1 | proA | OG2516_03969 | OG2516_03964 | Streptomycin phosphotransferase, streptomycin-resistance; COG3570 Streptomycin 6-kinase. | Gamma-glutamyl phosphate reductase GPR; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | 0.636 |
| EAR51022.1 | proB | OG2516_03969 | OG2516_03974 | Streptomycin phosphotransferase, streptomycin-resistance; COG3570 Streptomycin 6-kinase. | Gamma-glutamyl kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. | 0.773 |
| EAR52866.1 | EAR50080.1 | OG2516_10401 | OG2516_06404 | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | Bifunctional PutA protein; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | 0.916 |
| EAR52866.1 | argD | OG2516_10401 | OG2516_14166 | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | COG4992 Ornithine/acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. | 0.693 |
| EAR52866.1 | proA | OG2516_10401 | OG2516_03964 | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | Gamma-glutamyl phosphate reductase GPR; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | 0.933 |
| EAR52866.1 | proB | OG2516_10401 | OG2516_03974 | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | Gamma-glutamyl kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. | 0.747 |
| EAR52866.1 | proC | OG2516_10401 | OG2516_14301 | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | 0.631 |
| EAR52866.1 | prs | OG2516_10401 | OG2516_17076 | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | Phosphoribosyl pyrophosphate synthetase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.601 |
| EAR52866.1 | ribB | OG2516_10401 | OG2516_05763 | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | Bifunctional GTP cyclohydrolaseII/3,4-dihydroxy-2butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.412 |
| argD | EAR50080.1 | OG2516_14166 | OG2516_06404 | COG4992 Ornithine/acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. | Bifunctional PutA protein; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | 0.919 |
| argD | EAR52866.1 | OG2516_14166 | OG2516_10401 | COG4992 Ornithine/acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | 0.693 |
| argD | proA | OG2516_14166 | OG2516_03964 | COG4992 Ornithine/acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. | Gamma-glutamyl phosphate reductase GPR; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | 0.751 |
| argD | proB | OG2516_14166 | OG2516_03974 | COG4992 Ornithine/acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. | Gamma-glutamyl kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. | 0.807 |