Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EAR50562.1Nitrogen metabolism transcriptional regulator, NtrC; COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains. (456 aa)    
Predicted Functional Partners:
EAR50563.1
Nitrogen regulation protein NtrB; COG3852 Signal transduction histidine kinase, nitrogen specific.
 0.996
EAR50848.1
PAS; COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain.
  
 0.961
EAR50849.1
COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain.
  
 0.954
EAR51560.1
Two-component sensor histidine kinase; COG2203 FOG: GAF domain.
  
 0.917
EAR50561.1
COG5000 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation.
 
 0.897
EAR51152.1
Hypothetical protein; COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain.
  
 0.889
EAR51016.1
PAS sensor Signal Tranduction Histidine Kinase; COG2202 FOG: PAS/PAC domain.
 
 0.883
EAR49853.1
Signal transduction histidine kinase; COG2202 FOG: PAS/PAC domain.
 
 0.877
EAR50564.1
tRNA-dihydrouridine synthase, putative; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.
     
 0.812
EAR52102.1
Response regulator/sensor histidine kinase; COG2202 FOG: PAS/PAC domain.
   
 0.800
Your Current Organism:
Oceanicola granulosus
NCBI taxonomy Id: 314256
Other names: O. granulosus HTCC2516, Oceanicola granulosus HTCC2516, Oceanicola granulosus KCTC 12143, Oceanicola granulosus str. HTCC2516, Oceanicola granulosus strain HTCC2516
Server load: low (18%) [HD]