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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pepALeucyl aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides. (489 aa)    
Predicted Functional Partners:
EAR52616.1
COG0308 Aminopeptidase N.
  
 0.901
EAR50176.1
COG2927 DNA polymerase III, chi subunit.
  
    0.900
EAR49662.1
Probable gamma-glutamyltranspeptidase; COG0405 Gamma-glutamyltransferase.
  
  
 0.888
gshB
COG0189 Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase); Belongs to the prokaryotic GSH synthase family.
   
 
 0.880
EAR50525.1
Cytosol aminopeptidase family protein; COG0260 Leucyl aminopeptidase; Belongs to the peptidase M17 family.
  
  
 
0.875
EAR50481.1
Putative aminotransferase; COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities.
  
 
  0.847
glyA
Hypothetical protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
    
 0.780
glyA-2
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
    
 0.780
EAR52681.1
Rhodanese domain protein/cystathionine beta-lyase; COG0607 Rhodanese-related sulfurtransferase.
   
  0.769
EAR51069.1
COG0031 Cysteine synthase.
    
  0.745
Your Current Organism:
Oceanicola granulosus
NCBI taxonomy Id: 314256
Other names: O. granulosus HTCC2516, Oceanicola granulosus HTCC2516, Oceanicola granulosus KCTC 12143, Oceanicola granulosus str. HTCC2516, Oceanicola granulosus strain HTCC2516
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