node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EAR50224.1 | EAR52508.1 | OG2516_12619 | OG2516_05353 | COG0246 Mannitol-1-phosphate/altronate dehydrogenases. | Hypothetical protein; COG1072 Panthothenate kinase. | 0.483 |
EAR50509.1 | EAR52508.1 | OG2516_09700 | OG2516_05353 | D-mannonate oxidoreductase; COG0246 Mannitol-1-phosphate/altronate dehydrogenases. | Hypothetical protein; COG1072 Panthothenate kinase. | 0.546 |
EAR50688.1 | EAR52508.1 | OG2516_06312 | OG2516_05353 | Fructose-1,6-bisphosphatase, class II; COG1494 Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins. | Hypothetical protein; COG1072 Panthothenate kinase. | 0.551 |
EAR50931.1 | EAR52508.1 | OG2516_13701 | OG2516_05353 | Phosphopantothenoylcysteine synthase/decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Hypothetical protein; COG1072 Panthothenate kinase. | 0.885 |
EAR50931.1 | coaD | OG2516_13701 | OG2516_03003 | Phosphopantothenoylcysteine synthase/decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.933 |
EAR50931.1 | coaX | OG2516_13701 | OG2516_02838 | Phosphopantothenoylcysteine synthase/decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Transcriptional activator, Baf family protein; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | 0.891 |
EAR50931.1 | panC | OG2516_13701 | OG2516_13776 | Phosphopantothenoylcysteine synthase/decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.924 |
EAR52037.1 | EAR52508.1 | OG2516_13469 | OG2516_05353 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | Hypothetical protein; COG1072 Panthothenate kinase. | 0.475 |
EAR52037.1 | deoA | OG2516_13469 | OG2516_13474 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. | 0.999 |
EAR52508.1 | EAR50224.1 | OG2516_05353 | OG2516_12619 | Hypothetical protein; COG1072 Panthothenate kinase. | COG0246 Mannitol-1-phosphate/altronate dehydrogenases. | 0.483 |
EAR52508.1 | EAR50509.1 | OG2516_05353 | OG2516_09700 | Hypothetical protein; COG1072 Panthothenate kinase. | D-mannonate oxidoreductase; COG0246 Mannitol-1-phosphate/altronate dehydrogenases. | 0.546 |
EAR52508.1 | EAR50688.1 | OG2516_05353 | OG2516_06312 | Hypothetical protein; COG1072 Panthothenate kinase. | Fructose-1,6-bisphosphatase, class II; COG1494 Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins. | 0.551 |
EAR52508.1 | EAR50931.1 | OG2516_05353 | OG2516_13701 | Hypothetical protein; COG1072 Panthothenate kinase. | Phosphopantothenoylcysteine synthase/decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.885 |
EAR52508.1 | EAR52037.1 | OG2516_05353 | OG2516_13469 | Hypothetical protein; COG1072 Panthothenate kinase. | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | 0.475 |
EAR52508.1 | coaD | OG2516_05353 | OG2516_03003 | Hypothetical protein; COG1072 Panthothenate kinase. | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.899 |
EAR52508.1 | coaX | OG2516_05353 | OG2516_02838 | Hypothetical protein; COG1072 Panthothenate kinase. | Transcriptional activator, Baf family protein; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | 0.492 |
EAR52508.1 | deoA | OG2516_05353 | OG2516_13474 | Hypothetical protein; COG1072 Panthothenate kinase. | Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. | 0.446 |
EAR52508.1 | panC | OG2516_05353 | OG2516_13776 | Hypothetical protein; COG1072 Panthothenate kinase. | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.863 |
EAR52508.1 | pyrF | OG2516_05353 | OG2516_12566 | Hypothetical protein; COG1072 Panthothenate kinase. | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.449 |
coaD | EAR50931.1 | OG2516_03003 | OG2516_13701 | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Phosphopantothenoylcysteine synthase/decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.933 |