| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAR49884.1 | EAR51986.1 | OG2516_14156 | OG2516_13214 | Flagellar motor protein; COG1196 Chromosome segregation ATPases. | COG0514 Superfamily II DNA helicase. | 0.825 |
| EAR49884.1 | EAR51987.1 | OG2516_14156 | OG2516_13219 | Flagellar motor protein; COG1196 Chromosome segregation ATPases. | COG0210 Superfamily I DNA and RNA helicases. | 0.825 |
| EAR49884.1 | EAR51988.1 | OG2516_14156 | OG2516_13224 | Flagellar motor protein; COG1196 Chromosome segregation ATPases. | COG0210 Superfamily I DNA and RNA helicases. | 0.825 |
| EAR49884.1 | parE | OG2516_14156 | OG2516_05977 | Flagellar motor protein; COG1196 Chromosome segregation ATPases. | DNA topoisomerase IV subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily. | 0.735 |
| EAR50755.1 | EAR51986.1 | OG2516_10139 | OG2516_13214 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | COG0514 Superfamily II DNA helicase. | 0.994 |
| EAR50755.1 | EAR51987.1 | OG2516_10139 | OG2516_13219 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | COG0210 Superfamily I DNA and RNA helicases. | 0.994 |
| EAR50755.1 | EAR51988.1 | OG2516_10139 | OG2516_13224 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | COG0210 Superfamily I DNA and RNA helicases. | 0.994 |
| EAR50755.1 | EAR52914.1 | OG2516_10139 | OG2516_10641 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Putative DNA topoisomerase I protein; COG3569 Topoisomerase IB. | 0.602 |
| EAR50755.1 | gyrA | OG2516_10139 | OG2516_02743 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.507 |
| EAR50755.1 | parC | OG2516_10139 | OG2516_08618 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA topoisomerase IV subunit A; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily. | 0.485 |
| EAR50755.1 | parE | OG2516_10139 | OG2516_05977 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA topoisomerase IV subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily. | 0.809 |
| EAR50755.1 | recF | OG2516_10139 | OG2516_10144 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Recombination protein F; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. | 0.981 |
| EAR51986.1 | EAR49884.1 | OG2516_13214 | OG2516_14156 | COG0514 Superfamily II DNA helicase. | Flagellar motor protein; COG1196 Chromosome segregation ATPases. | 0.825 |
| EAR51986.1 | EAR50755.1 | OG2516_13214 | OG2516_10139 | COG0514 Superfamily II DNA helicase. | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.994 |
| EAR51986.1 | EAR51987.1 | OG2516_13214 | OG2516_13219 | COG0514 Superfamily II DNA helicase. | COG0210 Superfamily I DNA and RNA helicases. | 0.999 |
| EAR51986.1 | EAR51988.1 | OG2516_13214 | OG2516_13224 | COG0514 Superfamily II DNA helicase. | COG0210 Superfamily I DNA and RNA helicases. | 0.999 |
| EAR51986.1 | EAR52914.1 | OG2516_13214 | OG2516_10641 | COG0514 Superfamily II DNA helicase. | Putative DNA topoisomerase I protein; COG3569 Topoisomerase IB. | 0.949 |
| EAR51986.1 | gyrA | OG2516_13214 | OG2516_02743 | COG0514 Superfamily II DNA helicase. | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.433 |
| EAR51986.1 | parC | OG2516_13214 | OG2516_08618 | COG0514 Superfamily II DNA helicase. | DNA topoisomerase IV subunit A; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily. | 0.433 |
| EAR51986.1 | parE | OG2516_13214 | OG2516_05977 | COG0514 Superfamily II DNA helicase. | DNA topoisomerase IV subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily. | 0.793 |
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