| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAR50651.1 | EAR50652.1 | OG2516_06127 | OG2516_06132 | C4-dicarboxylate transport transcriptional regulatory protein DctD; COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains. | C4-dicarboxylate transport sensor protein DctB, putative; COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system. | 0.978 |
| EAR50651.1 | EAR50654.1 | OG2516_06127 | OG2516_06142 | C4-dicarboxylate transport transcriptional regulatory protein DctD; COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains. | Hypothetical protein. | 0.503 |
| EAR50651.1 | purQ | OG2516_06127 | OG2516_06137 | C4-dicarboxylate transport transcriptional regulatory protein DctD; COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains. | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | 0.503 |
| EAR50652.1 | EAR50651.1 | OG2516_06132 | OG2516_06127 | C4-dicarboxylate transport sensor protein DctB, putative; COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system. | C4-dicarboxylate transport transcriptional regulatory protein DctD; COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains. | 0.978 |
| EAR50652.1 | EAR50654.1 | OG2516_06132 | OG2516_06142 | C4-dicarboxylate transport sensor protein DctB, putative; COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system. | Hypothetical protein. | 0.535 |
| EAR50652.1 | purC | OG2516_06132 | OG2516_06152 | C4-dicarboxylate transport sensor protein DctB, putative; COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system. | COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; Belongs to the SAICAR synthetase family. | 0.471 |
| EAR50652.1 | purQ | OG2516_06132 | OG2516_06137 | C4-dicarboxylate transport sensor protein DctB, putative; COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system. | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | 0.611 |
| EAR50652.1 | purS | OG2516_06132 | OG2516_06147 | C4-dicarboxylate transport sensor protein DctB, putative; COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system. | Phosphoribosylformylglycinamidine synthase, PurS protein; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought [...] | 0.488 |
| EAR50654.1 | EAR50651.1 | OG2516_06142 | OG2516_06127 | Hypothetical protein. | C4-dicarboxylate transport transcriptional regulatory protein DctD; COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains. | 0.503 |
| EAR50654.1 | EAR50652.1 | OG2516_06142 | OG2516_06132 | Hypothetical protein. | C4-dicarboxylate transport sensor protein DctB, putative; COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system. | 0.535 |
| EAR50654.1 | purC | OG2516_06142 | OG2516_06152 | Hypothetical protein. | COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; Belongs to the SAICAR synthetase family. | 0.541 |
| EAR50654.1 | purQ | OG2516_06142 | OG2516_06137 | Hypothetical protein. | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | 0.773 |
| EAR50654.1 | purS | OG2516_06142 | OG2516_06147 | Hypothetical protein. | Phosphoribosylformylglycinamidine synthase, PurS protein; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought [...] | 0.548 |
| purC | EAR50652.1 | OG2516_06152 | OG2516_06132 | COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; Belongs to the SAICAR synthetase family. | C4-dicarboxylate transport sensor protein DctB, putative; COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system. | 0.471 |
| purC | EAR50654.1 | OG2516_06152 | OG2516_06142 | COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; Belongs to the SAICAR synthetase family. | Hypothetical protein. | 0.541 |
| purC | purQ | OG2516_06152 | OG2516_06137 | COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; Belongs to the SAICAR synthetase family. | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | 0.991 |
| purC | purS | OG2516_06152 | OG2516_06147 | COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; Belongs to the SAICAR synthetase family. | Phosphoribosylformylglycinamidine synthase, PurS protein; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought [...] | 0.989 |
| purQ | EAR50651.1 | OG2516_06137 | OG2516_06127 | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | C4-dicarboxylate transport transcriptional regulatory protein DctD; COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains. | 0.503 |
| purQ | EAR50652.1 | OG2516_06137 | OG2516_06132 | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | C4-dicarboxylate transport sensor protein DctB, putative; COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system. | 0.611 |
| purQ | EAR50654.1 | OG2516_06137 | OG2516_06142 | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | Hypothetical protein. | 0.773 |