| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAR50657.1 | EAR50659.1 | OG2516_06157 | OG2516_06167 | COG3064 Membrane protein involved in colicin uptake. | COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain. | 0.661 |
| EAR50657.1 | atpA | OG2516_06157 | OG2516_08973 | COG3064 Membrane protein involved in colicin uptake. | ATP synthase subunit A; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. | 0.978 |
| EAR50657.1 | atpB | OG2516_06157 | OG2516_09373 | COG3064 Membrane protein involved in colicin uptake. | ATP synthase subunit A; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. Belongs to the ATPase A chain family. | 0.939 |
| EAR50657.1 | atpC | OG2516_06157 | OG2516_08958 | COG3064 Membrane protein involved in colicin uptake. | ATP synthase F1, epsilon subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. | 0.939 |
| EAR50657.1 | atpD | OG2516_06157 | OG2516_08963 | COG3064 Membrane protein involved in colicin uptake. | ATP synthase subunit B; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. | 0.978 |
| EAR50657.1 | atpE | OG2516_06157 | OG2516_09368 | COG3064 Membrane protein involved in colicin uptake. | ATP synthase subunit C; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. | 0.947 |
| EAR50657.1 | atpG | OG2516_06157 | OG2516_08968 | COG3064 Membrane protein involved in colicin uptake. | ATP synthase subunit C; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. | 0.978 |
| EAR50657.1 | atpH | OG2516_06157 | OG2516_08978 | COG3064 Membrane protein involved in colicin uptake. | ATP synthase delta chain; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. | 0.939 |
| EAR50657.1 | purC | OG2516_06157 | OG2516_06152 | COG3064 Membrane protein involved in colicin uptake. | COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; Belongs to the SAICAR synthetase family. | 0.694 |
| EAR50657.1 | purS | OG2516_06157 | OG2516_06147 | COG3064 Membrane protein involved in colicin uptake. | Phosphoribosylformylglycinamidine synthase, PurS protein; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought [...] | 0.690 |
| EAR50659.1 | EAR50657.1 | OG2516_06167 | OG2516_06157 | COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain. | COG3064 Membrane protein involved in colicin uptake. | 0.661 |
| EAR50659.1 | purC | OG2516_06167 | OG2516_06152 | COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain. | COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; Belongs to the SAICAR synthetase family. | 0.471 |
| EAR50659.1 | purS | OG2516_06167 | OG2516_06147 | COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain. | Phosphoribosylformylglycinamidine synthase, PurS protein; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought [...] | 0.453 |
| atpA | EAR50657.1 | OG2516_08973 | OG2516_06157 | ATP synthase subunit A; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. | COG3064 Membrane protein involved in colicin uptake. | 0.978 |
| atpA | atpB | OG2516_08973 | OG2516_09373 | ATP synthase subunit A; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. | ATP synthase subunit A; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. Belongs to the ATPase A chain family. | 0.999 |
| atpA | atpC | OG2516_08973 | OG2516_08958 | ATP synthase subunit A; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. | ATP synthase F1, epsilon subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. | 0.999 |
| atpA | atpD | OG2516_08973 | OG2516_08963 | ATP synthase subunit A; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. | ATP synthase subunit B; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. | 0.999 |
| atpA | atpE | OG2516_08973 | OG2516_09368 | ATP synthase subunit A; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. | ATP synthase subunit C; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. | 0.999 |
| atpA | atpG | OG2516_08973 | OG2516_08968 | ATP synthase subunit A; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. | ATP synthase subunit C; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. | 0.999 |
| atpA | atpH | OG2516_08973 | OG2516_08978 | ATP synthase subunit A; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. | ATP synthase delta chain; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. | 0.999 |