| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAR50383.1 | EAR50430.1 | OG2516_16741 | OG2516_08833 | Dihydroorotase, multifunctional complex type; COG0044 Dihydroorotase and related cyclic amidohydrolases. | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.982 |
| EAR50383.1 | EAR50682.1 | OG2516_16741 | OG2516_06282 | Dihydroorotase, multifunctional complex type; COG0044 Dihydroorotase and related cyclic amidohydrolases. | COG2233 Xanthine/uracil permeases. | 0.902 |
| EAR50383.1 | EAR50684.1 | OG2516_16741 | OG2516_06292 | Dihydroorotase, multifunctional complex type; COG0044 Dihydroorotase and related cyclic amidohydrolases. | Polysaccharide deacetylase family protein; COG0726 Predicted xylanase/chitin deacetylase. | 0.815 |
| EAR50383.1 | EAR52963.1 | OG2516_16741 | OG2516_10886 | Dihydroorotase, multifunctional complex type; COG0044 Dihydroorotase and related cyclic amidohydrolases. | Dihydropyrimidinase; COG0044 Dihydroorotase and related cyclic amidohydrolases. | 0.858 |
| EAR50383.1 | EAR52970.1 | OG2516_16741 | OG2516_10921 | Dihydroorotase, multifunctional complex type; COG0044 Dihydroorotase and related cyclic amidohydrolases. | COG0167 Dihydroorotate dehydrogenase. | 0.982 |
| EAR50383.1 | carA | OG2516_16741 | OG2516_07340 | Dihydroorotase, multifunctional complex type; COG0044 Dihydroorotase and related cyclic amidohydrolases. | COG0505 Carbamoylphosphate synthase small subunit; Belongs to the CarA family. | 0.993 |
| EAR50383.1 | carB | OG2516_16741 | OG2516_13941 | Dihydroorotase, multifunctional complex type; COG0044 Dihydroorotase and related cyclic amidohydrolases. | COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); Belongs to the CarB family. | 0.982 |
| EAR50383.1 | pyrB | OG2516_16741 | OG2516_16761 | Dihydroorotase, multifunctional complex type; COG0044 Dihydroorotase and related cyclic amidohydrolases. | COG0540 Aspartate carbamoyltransferase, catalytic chain; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.999 |
| EAR50383.1 | pyrE | OG2516_16741 | OG2516_01736 | Dihydroorotase, multifunctional complex type; COG0044 Dihydroorotase and related cyclic amidohydrolases. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.931 |
| EAR50383.1 | pyrF | OG2516_16741 | OG2516_12566 | Dihydroorotase, multifunctional complex type; COG0044 Dihydroorotase and related cyclic amidohydrolases. | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.919 |
| EAR50430.1 | EAR50383.1 | OG2516_08833 | OG2516_16741 | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | Dihydroorotase, multifunctional complex type; COG0044 Dihydroorotase and related cyclic amidohydrolases. | 0.982 |
| EAR50430.1 | EAR50682.1 | OG2516_08833 | OG2516_06282 | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | COG2233 Xanthine/uracil permeases. | 0.860 |
| EAR50430.1 | EAR52963.1 | OG2516_08833 | OG2516_10886 | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | Dihydropyrimidinase; COG0044 Dihydroorotase and related cyclic amidohydrolases. | 0.980 |
| EAR50430.1 | EAR52970.1 | OG2516_08833 | OG2516_10921 | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | COG0167 Dihydroorotate dehydrogenase. | 0.859 |
| EAR50430.1 | carA | OG2516_08833 | OG2516_07340 | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | COG0505 Carbamoylphosphate synthase small subunit; Belongs to the CarA family. | 0.939 |
| EAR50430.1 | carB | OG2516_08833 | OG2516_13941 | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); Belongs to the CarB family. | 0.962 |
| EAR50430.1 | pyrB | OG2516_08833 | OG2516_16761 | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | COG0540 Aspartate carbamoyltransferase, catalytic chain; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.947 |
| EAR50430.1 | pyrE | OG2516_08833 | OG2516_01736 | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.987 |
| EAR50430.1 | pyrF | OG2516_08833 | OG2516_12566 | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.929 |
| EAR50682.1 | EAR50383.1 | OG2516_06282 | OG2516_16741 | COG2233 Xanthine/uracil permeases. | Dihydroorotase, multifunctional complex type; COG0044 Dihydroorotase and related cyclic amidohydrolases. | 0.902 |