| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAR49887.1 | EAR50383.1 | OG2516_14171 | OG2516_16741 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | Dihydroorotase, multifunctional complex type; COG0044 Dihydroorotase and related cyclic amidohydrolases. | 0.500 |
| EAR49887.1 | argG | OG2516_14171 | OG2516_11381 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | COG0137 Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | 0.997 |
| EAR49887.1 | carA | OG2516_14171 | OG2516_07340 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | COG0505 Carbamoylphosphate synthase small subunit; Belongs to the CarA family. | 0.997 |
| EAR49887.1 | carB | OG2516_14171 | OG2516_13941 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); Belongs to the CarB family. | 0.997 |
| EAR49887.1 | pyrB | OG2516_14171 | OG2516_16761 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | COG0540 Aspartate carbamoyltransferase, catalytic chain; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.904 |
| EAR50383.1 | EAR49887.1 | OG2516_16741 | OG2516_14171 | Dihydroorotase, multifunctional complex type; COG0044 Dihydroorotase and related cyclic amidohydrolases. | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | 0.500 |
| EAR50383.1 | EAR50430.1 | OG2516_16741 | OG2516_08833 | Dihydroorotase, multifunctional complex type; COG0044 Dihydroorotase and related cyclic amidohydrolases. | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.982 |
| EAR50383.1 | EAR52963.1 | OG2516_16741 | OG2516_10886 | Dihydroorotase, multifunctional complex type; COG0044 Dihydroorotase and related cyclic amidohydrolases. | Dihydropyrimidinase; COG0044 Dihydroorotase and related cyclic amidohydrolases. | 0.858 |
| EAR50383.1 | carA | OG2516_16741 | OG2516_07340 | Dihydroorotase, multifunctional complex type; COG0044 Dihydroorotase and related cyclic amidohydrolases. | COG0505 Carbamoylphosphate synthase small subunit; Belongs to the CarA family. | 0.993 |
| EAR50383.1 | carB | OG2516_16741 | OG2516_13941 | Dihydroorotase, multifunctional complex type; COG0044 Dihydroorotase and related cyclic amidohydrolases. | COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); Belongs to the CarB family. | 0.982 |
| EAR50383.1 | pyrB | OG2516_16741 | OG2516_16761 | Dihydroorotase, multifunctional complex type; COG0044 Dihydroorotase and related cyclic amidohydrolases. | COG0540 Aspartate carbamoyltransferase, catalytic chain; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.999 |
| EAR50383.1 | pyrE | OG2516_16741 | OG2516_01736 | Dihydroorotase, multifunctional complex type; COG0044 Dihydroorotase and related cyclic amidohydrolases. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.931 |
| EAR50430.1 | EAR50383.1 | OG2516_08833 | OG2516_16741 | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | Dihydroorotase, multifunctional complex type; COG0044 Dihydroorotase and related cyclic amidohydrolases. | 0.982 |
| EAR50430.1 | EAR52963.1 | OG2516_08833 | OG2516_10886 | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | Dihydropyrimidinase; COG0044 Dihydroorotase and related cyclic amidohydrolases. | 0.980 |
| EAR50430.1 | carA | OG2516_08833 | OG2516_07340 | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | COG0505 Carbamoylphosphate synthase small subunit; Belongs to the CarA family. | 0.939 |
| EAR50430.1 | carB | OG2516_08833 | OG2516_13941 | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); Belongs to the CarB family. | 0.962 |
| EAR50430.1 | purF | OG2516_08833 | OG2516_04718 | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.410 |
| EAR50430.1 | pyrB | OG2516_08833 | OG2516_16761 | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | COG0540 Aspartate carbamoyltransferase, catalytic chain; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.947 |
| EAR50430.1 | pyrE | OG2516_08833 | OG2516_01736 | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.987 |
| EAR52963.1 | EAR50383.1 | OG2516_10886 | OG2516_16741 | Dihydropyrimidinase; COG0044 Dihydroorotase and related cyclic amidohydrolases. | Dihydroorotase, multifunctional complex type; COG0044 Dihydroorotase and related cyclic amidohydrolases. | 0.858 |