| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAR50848.1 | EAR50849.1 | OG2516_00055 | OG2516_00060 | PAS; COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain. | COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain. | 0.999 |
| EAR50848.1 | EAR51152.1 | OG2516_00055 | OG2516_14795 | PAS; COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain. | Hypothetical protein; COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain. | 0.999 |
| EAR50848.1 | gyrB | OG2516_00055 | OG2516_10164 | PAS; COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain. | DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.575 |
| EAR50848.1 | rpoD | OG2516_00055 | OG2516_04668 | PAS; COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain. | RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. | 0.817 |
| EAR50848.1 | ruvA | OG2516_00055 | OG2516_07697 | PAS; COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain. | Holliday junction DNA helicase motor protein; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.412 |
| EAR50848.1 | ruvB | OG2516_00055 | OG2516_07692 | PAS; COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain. | Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.828 |
| EAR50849.1 | EAR50848.1 | OG2516_00060 | OG2516_00055 | COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain. | PAS; COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain. | 0.999 |
| EAR50849.1 | EAR51152.1 | OG2516_00060 | OG2516_14795 | COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain. | Hypothetical protein; COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain. | 0.999 |
| EAR50849.1 | gyrB | OG2516_00060 | OG2516_10164 | COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain. | DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.511 |
| EAR50849.1 | rpoD | OG2516_00060 | OG2516_04668 | COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain. | RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. | 0.595 |
| EAR50849.1 | ruvB | OG2516_00060 | OG2516_07692 | COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain. | Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.790 |
| EAR51152.1 | EAR50848.1 | OG2516_14795 | OG2516_00055 | Hypothetical protein; COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain. | PAS; COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain. | 0.999 |
| EAR51152.1 | EAR50849.1 | OG2516_14795 | OG2516_00060 | Hypothetical protein; COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain. | COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain. | 0.999 |
| EAR51152.1 | rpoD | OG2516_14795 | OG2516_04668 | Hypothetical protein; COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain. | RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. | 0.472 |
| EAR51152.1 | ruvB | OG2516_14795 | OG2516_07692 | Hypothetical protein; COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain. | Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.762 |
| EAR52340.1 | EAR52341.1 | OG2516_07682 | OG2516_07687 | COG0824 Predicted thioesterase. | Hypothetical protein. | 0.855 |
| EAR52340.1 | ruvA | OG2516_07682 | OG2516_07697 | COG0824 Predicted thioesterase. | Holliday junction DNA helicase motor protein; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.704 |
| EAR52340.1 | ruvB | OG2516_07682 | OG2516_07692 | COG0824 Predicted thioesterase. | Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.775 |
| EAR52340.1 | ruvC | OG2516_07682 | OG2516_07702 | COG0824 Predicted thioesterase. | Holliday junction resolvase; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.743 |
| EAR52341.1 | EAR52340.1 | OG2516_07687 | OG2516_07682 | Hypothetical protein. | COG0824 Predicted thioesterase. | 0.855 |
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